CRO Unit 3 Exam Questions & Answers 2024/2025
medical oncology - ANSWERSspecialize in use of meds, such as chemo, hormones, and analgesics, in pain management of cancer
major functions of medical oncology - ANSWERSinterpret natural history of malignant diseases
apply chemo techniques
diag...
medical oncology - ANSWERSspecialize in use of meds, such as chemo, hormones, and analgesics, in pain
management of cancer
major functions of medical oncology - ANSWERSinterpret natural history of malignant diseases
apply chemo techniques
diagnose and manage complications of the disease
coordination of emotional, nutritional, and social support
medical oncologists must know... - ANSWERSmechanisms of action of the drug metabolism of the drug
involved and their effects on normal tissue
cytotoxic agents kill cancer according to - ANSWERSfirst order kinetics
first order kinetics means - ANSWERSa constant percentage of tumor cells rather than number are killed
given exposure to a drug
cell cycle specific drugs - ANSWERSinterfere with the sequence of activities a cell goes through to divide
into two identical daughter cells
if a cell cannot divide it... - ANSWERSlives out it's life span and dies
cytotoxic agents response is generally enhanced by - ANSWERSa large growth fraction
-large number of cells proceeding through mitosis
choosing agents that act at varying phases of the cell cycle _____ kill - ANSWERSincreases
, _____ growing normal tissues are also highly susceptible to cycle specific drugs - ANSWERSactively
examples of actively growing normal cells - ANSWERSbone marrow, gi tract, hair follicles
cell cycle non specific drugs - ANSWERSdrugs that affect cancer cells in all phases of life
not just during division
cancer cells are more immature and fragile than normal cells, so they are affected ______ than healthy
cells by non specific drugs - ANSWERSfar more
cell cycle nonspecific drugs are especially useful in killing cancer cells that are ______ growing -
ANSWERSslow
hormones make the environment.... - ANSWERSless hospitable for cancer cells, thus slowing down
growth
hormone for breast cancer - ANSWERSestrogen
hormones for prostate cancer - ANSWERStestosterone
choosing agents acting in different phases of cell cycle _____ tumor cell killing potential -
ANSWERSincreases
actively growing cells are ______ susceptible - ANSWERSmost
TP53 is a - ANSWERStumor suppressor gene
TP53 provides a cell cycle check point for controlling - ANSWERSDNA damage by slowing down the cell to
allow for repair or initiating apoptosis
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