ACE inhibitors reduce blood pressure by inhibiting the formation of what?
Angiotensin II
ARB reduces the effect of lowering blood pressure. - Answer: Angiotensin II.
How does DRI work? - ANSWER Reduce production of Angiotensin I.
What is the name of the only DRI medicine available to treat hypertension? -
ANSWER Aliskiren
What type of diuretic is HCTZ? - Answer: Thiazide.
Which osmotic diuretic can lower intracranial pressure when administered by a
parent? - ANSWER Mannitol
What is the MOA of loop diuretics? - ANSWER Blocks the reabsorption of Na and
Cl in Henle's ascending loop.
What kind of diuretics are bumetanide and torsemide? - ANSWER: Loop diuretics
What is the most serious side effect of ethacrynic acid? - ANSWER Ototoxicity.
Which diuretic is best for people with osteoporosis? - ANSWER Thiazide diuretics
can preserve calcium.
, Metolazone falls within what kind of diuretic? - Answer: Thiazide diuretics.
What is the mechanism of action for Esplerenone? - ANSWER Inhibits the
aldosterone receptor, which causes increased excretion of water and salt and
retention of potassium.
What is the difference between Spironolactone, Esplerenone, and
Trianterene/Amiloride? - ANSWER T and A directly block the function of the
sodium-potassium channel without using aldosterone.
Captopril, Enalapril, and Lisinopril fall under which medicine category? - Answer:
ACE inhibitors.
Are ACE inhibitors safe during pregnancy? - ANSWER No, they're teratogenic.
Why do ACE inhibitors induce a cough? - ANSWER ACE raises bradykinins,
which causes lung irritation.
Why should ACE inhibitors not be administered to renal patients? - ANSWER:
ACE inhibitors reverse the constriction of the efferent arteriole, therefore reducing
the GFR.
What are the medications with the ending -sartan? - Answer: ARBS (Angiotensin II
receptor blockers).
What are the advantages of using an ARB instead of an ACE inhibitor? -
ANSWER Lower likelihood of coughing due to decreased bradykinin generation in
the lungs.
Which area of the heart does Verapamil target? - ANSWER Verapamil is a calcium
channel blocker that works on the coronary arteries of the heart. The overall impact
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