Immunology Exam 1
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What are two examples of phagocytes? - answer Neutrophils (PMN-
polymorpho nuclear) and Macrophages (MO)
True or false: Monocytes are precursors of macrophages. - answer
True. Monocytes are found in blood but when they move into tissues,
they are macrophages.
What cells are important for parasite control, allergy, and
inflammation? - answer 1. mast cell (release histamine when activated)
2. eosinophil (similar function as mast cell but arrive at scene later)
3. basophil (uncommon; function unknown)
4. dendritic cell (internalize pathogens & active T-cells & help initiate
adaptive immune response-serving as a bridge)
,What are two types of lymphocytes? - answer T cells and B cells.
T or F: Plasma cells are B-cells that actively secrete antibodies. - answer
True.
What is the effector function? - answer A job that a cell has once it is
activated
Some functions of the immune response include: - answer a.
recognition of the pathogen or antigen
b. develop "effector" function
What are the main differences between innate immunity and adaptive
immunity? - answer Innate immunity: quicker response, use less
specific mechanisms to recognize pathogens, unable to eradicate the
pathogen completely, doesn't provide immunity for reinfection.
Define hematopoiesis. - answer Hematopoiesis is the generation of
blood cells.
T or F: Blood cells and certain tissue cells derive from a common
hematopoietic stem cell. - answer True. It's pluripotent & self-renewing
(can make many copies of itself)
, Immune cells go through which pathways? - answer Lymphoid and
myeloid pathways.
What are examples of granulocytes? - answer neutrophils, basophils,
and eosinophils. They are polymorphonuclear leukocytes that reside in
the blood.
What chemical signals drive the path the cell takes to its final fate? -
answer 1. colony stimulating factor (CSF) - GCSF (granulocyte colony
stimulating factor) --> drives the production of neutrophils
2. cytokines
3. growth factors
Blood cell development occurs where in the body? - answer fetal liver
or spleen, and bone marrow (adults only)
What does lymphoid progenitor differentiate into? - answer 1. B cells
2. T cells
3. Natural Killer (NK) cells
What does myeloid progenitor differentiate into? - answer 1. basophils
2. eosinophils
3. neutrophils
4. mast cells
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