Exam (elaborations)
Hbss Sickle Cell Anemia Questions And Answers With Verified Solutions 100% Correct!!!
- Module
- Institution
Hbss Sickle Cell Anemia Questions And Answers With Verified Solutions 100% Correct!!!
[Show more]
Seller
Follow
classhub
Reviews received
Content preview
Hbss Sickle Cell Anemia Questions AndAnswers With Verified Solutions 100%
Correct!!!
Clinical hallmarks of SCD - ANSWER✔✔ Vasooclusion and hemolysis
What are the atypical hemoglobin molecules called - ANSWER✔✔ Hemoglobin S
(HbS)
Definition of SCD - ANSWER✔✔ Complex group of autosomal recessive genetic
disorders associated with frequent and unpredictable crisis episodes
Normal adult Hgb contains how many alpha and beta chains - ANSWER✔✔ 2
alpha-globulin and 2 beta-globulin
A gene mutation in this subunit produces the HbS - ANSWER✔✔ Hemoglobin beta
subunit (HBB)
Hemoglobin S (HbS) is the abnormal version of what subunit - ANSWER✔✔ Beta-
globin
What is the gene mutation in HBB that produces HbS - ANSWER✔✔ Single
substitution of amino acid valine for glutamic acid at position 6 of the beta-
polypeptide chain
Differences between sickle cell trait and sickle cell disease - ANSWER✔✔ - Sickle
cell trait: heterozygous form
, - Sickle cell disease: homozygous
What is sickle cell trait? - ANSWER✔✔ The heterozygous form of SCD that is
asymptomatic
What is the acronym for sickle cell trait - ANSWER✔✔ HbAS (one normal HbA
gene and one abnormal HbS gene)
What is Sickle cell disease in comparison to sickle cell trait - ANSWER✔✔ There
are two HbS genes and no normal HbA genes
What is the acronym for sickle cell disease - ANSWER✔✔ HbSS (two abnormal
HbS genes and no normal HbA genes)
How many genotypes of SCD in the US? - ANSWER✔✔ 4
What are the 4 genotypes? - ANSWER✔✔ 1) Sickle Cell Anemia (HbSS)
2) Sickle Hemoglobin C (HbSC)
3) Two types of sickle-beta thalassemia (SB+ or SB° thalassemia)
What is the etiology of SCD? - ANSWER✔✔ Sickle cell hemoglobin S is transmitted
by an autosomal recessive gene
What is the etiology of SCD- who is it inherited from? - ANSWER✔✔ The parents
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller classhub. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £8.20. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
66579 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now