GMS 6551 Drug Studies with Complete Solutions
100% Verified
Drug targets - Correct Answer - enzymes
- receptors
- proteins
- DNA
- RNA
- carbohydrates
- lipids
Bacterial enzymes - Correct Answer - easier to target than human proteins
In vitro - Correct Answer - fast
- cheap
- test tube
In vivo - Correct Answer - complex
- expensive
- may mask things seen in test tube
- harmful to animals
Lead compound - Correct Answer - first compound that has deisred activity
SAR - Correct Answer - structure activity relationships
- optimize lead compounds
- makes drug better
- elimation of unneeded effects
Pharmacokinetics - Correct Answer - dose given & how often
- absorption
, - distribution
- metabolism
- excretion
- determined in vitro or in vivo
Pharmacodynamics - Correct Answer - what drug does to the body
- MOA
- potentcy
- efficacy
- toxicity
Pharmacogenetics - Correct Answer - how genetic makup impacts drug function
Pharmacotherapeutics - Correct Answer - how drugs are clinically used
Main targets - Correct Answer - receptors
- enzymes
Drug classification - Correct Answer - chemical properties (benzos)
- MOA (ACEI)
- disease or condition used to treat (analgesics)
- abuse potential
1) OTC
2) Prescription
3) Orphan drugs
Orpan drugs - Correct Answer - used to treat rare diseases
- usually funded by government
Schedule I - Correct Answer - high abuse potential
- no medical use
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