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Science Medicine Pharm Exam 2 Questions & answers latest update 2024/2025 with complete solution
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Science Medicine Pharm Exam 2 Questions & answers latest update 2024/2025 with complete solution
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1. Science2. Medicine
Science Medicine Pharm Exam 2
Terms in this set (91)
Original
Antimalarial Drugs: Indications
Used to kill Plasmodium organisms, the parasites that cause malaria
-Take this medicine with food or with a milky drink
Antimalarial Drugs: Indications
Some drugs are used for prophylaxis (prevention) against malaria.
Antimalarial Drugs: Contraindications
Drug allergy
Antimalarial Drugs: Contraindications
Tinnitus (ear ringing)
Antimalarial Drugs: Contraindications
Pregnancy (quinine)
Antimalarial Drugs: Contraindications
Severe renal, hepatic, or hematologic dysfunction
Antimalarial Drugs: Interactions
Patient who is receiving combinations of quinine derivative and quinineis at increased risk for cardiac
toxicity and convulsions; anti-folate drugs
Antimalarial Drugs: Adverse Effects
Primarily gastrointestinal (GI)
Antimalarial Drugs: Adverse Effects
Nausea
Antimalarial Drugs: Adverse Effects
Vomiting
Antimalarial Drugs: Adverse Effects
Diarrhea
Antimalarial Drugs: Adverse Effects
Anorexia
Antimalarial Drugs: Adverse Effects
Abdominal Pain
Antimalarial Drugs: Mechanism of Action
Aminoquinoline Derivatives:
Only Exoerythrocytic Antimalarial Drug (works in both phases)
is the only exoerythrocytic drug
Can be used in combination with Antimalarials for synergistic effects:
, Sulfonamides
Can be used in combination with Antimalarials for synergistic effects:
Tetracyclines
Can be used in combination with Antimalarials for synergistic effects
Clindamycin
Antimalarial Drugs:
-Has anti-inflammatory effects
Antimalarial Drugs:
-Decrease the excitability of both cardiac and skeletal muscles
Antimalarial Drugs:
Quinidine is still currently used to treat certain types of cardiac dysrhythmias.
Antimalarial Drugs:
Mefloquine Hydrochloride Black Box Warning
Possibility of neurologic and psychiatric adverse events
Antiprotozoal Drugs: Metronidazole (Flagyl) BLACK BOX WARNING
Carcinogen
Antiprotozoal Drugs: Metronidazole (Flagyl) ADVERSE EFFECTS
Metronidazole (Flagyl) ADVERSE EFFECTS
-Headache
-Dry Mouth
-Fatigue
-Metallic/Bitter taste in mouth
Antiprotozoal Drugs: Metronidazole (Flagyl) ADVERSE EFFECTS
Never Use With Alcohol
Including Mouthwash, Aftershave ect
Antiprotozoal Drugs: Atovaquone (Mepron) ADVERSE EFFECTS
pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting,
or yellow eyes or skin.
Antiprotozoal Drugs: CNS ADVERSE EFFECTS
headache, dizziness, ataxia, loss of coordination, and peripheral neuropathy related to drug effects
on the neurons
Antiprotozoal Drugs: Considerations For Children
-Many of these drugs do not have proven safety and efficacy in children
-extreme caution should be used.
Antiprotozoal Drugs: Considerations For Older Adult
-Older patients may be more susceptible to the adverse effects associated with these drugs.
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