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PSIO 303 EXAM 1 QUESTIONS WITH 100% SOLVED SOLUTIONS

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  • PSIO 303

Glycerophospholipids (GPLs): - amphipathic (having both hydrophilic and hydrophobic parts) are main lipid constituent of PM Contain glycerol backbone: 2 fatty acid tails in ester linkage A polar head group (that varies in size) A phosphate ester of another alcohol (choline, ethanolamine, serin...

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  • August 17, 2024
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  • PSIO 303
  • PSIO 303
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PSIO 303 EXAM 1
Glycerophospholipids (GPLs): - amphipathic (having both hydrophilic and hydrophobic parts)

are main lipid constituent of PM

Contain glycerol backbone:

2 fatty acid tails in ester linkage

A polar head group (that varies in size)

A phosphate ester of another alcohol (choline, ethanolamine, serine, or inositol)

GPLs can differ in polar head group, chain length, and saturation of bonds



Common cell structures called organelles are either membrane bound or non membrane bound. Choose
the following list that contains only membrane bound organelles. - nucleus, endoplasmic
reticulum, lysosome, mitochondrion



Mitochondria - making ATP by breaking down sugar



plasma membrane (cell membrane) - -Provides protection and a fixed environment for the cell



-Transports nutrients into the cell and transports toxic substance outside of the cell



Nucleus - Protecting, controlling access to DNA



Golgi - Modifying polypeptide chains; sorting, shipping proteins and lipids



Ribosomes - Assembling polypeptide chains



Lysosomes - Intracellular digestion; break down excess/ worn out cell parts or viruses & bacteria



Peroxisomes - Neutralization of toxins

,Homeostasis - self regulating process by which biological systems maintain stability by adjusting

to changing external conditions



Body temperature, blood pH, tissue oxygenation, cell size, cytoplasmic composition



Cell Theory - All living things are made up of cells



the cell is a structural and functional unit of all living things



All cells come from pre-existing cells



Cells contain hereditary information which is passed from cell to cell during division



All cells are basically the same in chemical composition



All energy flow of life occur within cells



Needs for cells to communicate - Sense and respond to other cells



Coordinate actions



Develop specialized functions (muscles, nerve, leukocytes)



Modes of cellular communication - Endocrine: cell in one part of the body sends signal

(hormone) to distant target cells



Paracrine: cell-cell communication

, Autocrine: cell stimulates itself



When plasma glucose concentration increases, cells in the pancreas release insulin. Insulin causes a
pattern of responses that decreases glucose concentration. This is an example of - Homeostasis
maintained by a negative feedback loop



What is your best estimate for the diameter of a pancreatic beta cell? - 10 microns



Describe the structure of the plasma membrane (PM) - Phospholipid bilayer: in an aqueous
environment:

Polar (hydrophilic) head groups orient TOWARD polar water

Nonpolar (hydrophobic) tail groups orient AWAY from water

Forms phospholipid bilayer which is the structure of the PM




Sphingolipids - Amphipathic

Sphingosine backbone:

1 fatty acid tail in amide

1 polar head group (carbohydrate or phosphate ester of another alcohol like choline or ethanolamine)



Cholesterol - Biggest function: alters fluidity



Wedges into bilayer by interacting with first few hydrocarbon groups of phospholipid tails (hydrophobic
region) and alters fluidity of lipid bilayer



Is also amphipathic, a sterol ( group of naturally occurring unsaturated steroid alcohols), and essential
membrane component



Membrane fluidity - Depends on lipid composition (saturation of hydrocarbon or lipid chains)\

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