NUR228 - HYPERSENSITIVITY EXAM
QUESTIONS AND ANSWERS
What is hypersensitivity? - ANSWER Inappropriate triggering of normal immune
ANSWER.
Excess (overproduction)
OR
Causes negative consequences on the body.
What are the basic causes of hypersensitivity? - ANSWER Antigen-antibody
ANSWER or antigen-lymphocyte interaction.
What are the four kinds of hypersensitivity? - Types I, II, and III (mediated by
antibodies produced by B cells, which when activated form plasma cells).
Type IV (mediated by T lymphocytes).
Which kind of hypersensitivity is mediated by antibodies? - Answer Types I, II,
and III.
What types of hypersensitivity are mediated by T cells? - Answer Type IV.
What is Type 1 Hypersensitivity? - ANSWER An immediate reaction occurs upon
antigen sensitization.
What are some types of antigens? - ANSWER Environmental (pet dander, bee
stings), Food (nuts, shellfish, eggs), and Medicine (penicillin, contrast dye).
, What are the causes of Type I hypersensitivity? - ANSWER Genetic relationship,
with a greater likelihood if one or both parents are allergic.
Which cells are involved in Type I hypersensitivity? - ANSWER B lymphocytes
produce IgE antibodies, which bind to mast cells.
What is the function of mast cells in Type I hypersensitivity? - ANSWER Mast
cells circulate throughout the body as part of the immune system.
What are the clinical signs of strong vasodilation? - ANSWER Stuffy nose, Lower
blood pressure, Wheals on skin
What are the clinical signs of enhanced vascular permeability? - ANSWER Edema,
runny nose.
What are the clinical signs of bronchial smooth muscle constriction? - ANSWER
breathing issues, wheezing
What are the clinical effects of activating irritating receptors? - ANSWER Itching
(pruritis).
What are atopic reactions? - ANSWER Inheritance of allergy sensitivity.
What are some types of atopic reactions? - ANSWER Allergic rhinitis, asthma, and
urticaria.
What are the most common causes of atopic reactions? - ANSWER Pollen, dust,
mold, and animal dander.
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