APEA STD's and STI's
test (46 questions and
answers)
Fever (96%)
Pharyngitis (70%)
Nonpruritic macular skin rash (70%)
Malaise
Headache
Lymphadenopathy (74%) - answer HIV initial
infection usual duration less than 14 days?
If high index of suspicion for HIV:
NAT* HIV-1 RNA assay (Aptima) (detects viral load
and HIV)
NOTE: CDC does not recommend NAT for diagnosis
SO if positive+, perform another HIV test
HIV 1/ 2 antigen/antibody immunoassay *NAT =
HIV-1 nucleic acid test = RNA qualitative assay =
Aptima - answer HIV TEST?
• 30% with a history of hepatitis C
, • 8% with a history of hepatitis B
• Liver disease progresses faster and affects the
choice of antiretroviral therapy
• TB: HIV is a significant risk factor for reactivation
of latent TB
• History of STIs - answer Primary Care of HIV-
Infected Adults — History?
• Need pneumococcal, tetanus, hep A/B; flu
annually
• Never administer live or attenuated vaccines!!!!!
• Consider immunization for close contacts
(exceptions: oral polio, smallpox) - answer
Primary Care of HIV-Infected Adults —
Immunizations?
• CD4 count-baseline; repeat once and usually q 3-
4 months (count determines need for prophylaxis
against opportunistic infections)
• Viral load: need baseline and q 3-4 months (if on
ART, goal is undetectable viral load within 16-24
weeks of therapy)
• Screen for hepatitis: A, B, C
• Glucose and lipid panel (consequence of ART use)
• STD assessment - answer Primary Care of HIV-
Infected Adults labs?
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