Hormone responsible for anabolism in the carbohydrate pathway correct answers insulin
What is the minimum number of samples to obtain a good reference range? correct answers 40
The pH of the body is kept relatively constant due to the presence of: correct answers HCO3 and Na
The most co...
Hormone responsible for anabolism in the carbohydrate pathway correct answers
insulin
What is the minimum number of samples to obtain a good reference range? correct
answers 40
The pH of the body is kept relatively constant due to the presence of: correct answers
HCO3 and Na
The most common carbohydrate that is measured as a biochemical marker of disease
is: correct answers glucose
The ability of a chemical away to detect or quantify an analyte without significant
interference or cross-reacting substance is: correct answers analytical specificity
A calcium (Ca++) concentration of 4.0 mg/dL is equivalent to what mEq/L
concentration? (Atomic mass Ca = 40.08 g/mole) correct answers 2 mEq/L
Fatty acids are utilized by the human body for energy when glucose is not available.
The breakdown products of beta-oxidation of fatty acids are called: correct answers
Ketones
The two most common lipoprotein-cholesterol molecules that are used in tandem to
determine risk for coronary artery disease are: correct answers HDL and LDL
The organ that directs plasma protein concentrations is: correct answers liver
The percentage of a normally distributed population that is expected to fall outside of 2
standard deviations is: correct answers 5%
A 95% confidence limit for cholesterol precision is 1300-1400 mg/L. The coefficient of
variation for this methodology is: correct answers 1.85%
Type I water has a resistivity in mega ohms/cm at 25 degrees C of 10 or more. What
requires Type I water? correct answers Trace metal analysis
According to CLSI standards, when should Type II water be used? correct answers
Quality control prep
Characteristics of a Mohr pipet include: correct answers Calibrated "to deliver" stated
volume at 25 degrees
,What is not true regarding capillary blood? correct answers It is more similar to venous
than arterial blood for concentrations of analytes
A 1/21 dilution is made using correct answers 50 uL of sample + 1 mL of diluent
The main reason that measurement of enzymes in serum/plasma/tissue is done to
assess: correct answers tissue damage
The frequency distribution curve of symmetrically distributed data will contain what % of
the plotted values from +1 standard deviation to -1 standard deviation? correct answers
68.2%
The best index of within-day precision of protein values (at level 1 control) on the
manual biuret protein assay is determined by looking at: correct answers The
calculated coefficient of variation of the control values for that day
A sensitive test is one which: correct answers can detect small amounts of or slight
changes in analyte
What type of pipet is designed to deliver its entire volume when "blown out"? correct
answers Serological pipet
What pipet will accurately deliver 10 uL of sample? correct answers A 0.01 mL
micropipet (0.2% error)
For serum creatinine it is recommended that a protein-free filtrate be prepared using the
following volumes of reagents and serum:
Patient serum: 1.0 mL
H2O: 7.0 mL
0.67 N H2SO4: 1.0 mL
10% Na2WO4: 1.0 mL
What is the dilution made on the patient serum with these reagents? correct answers
1:10
The ____ pipet contains multiple markings for the measurement of liquids but is not
graduated to the tip. correct answers Mohr
The least amount of, or the lease change in the concentration of an analyte is defined
as: correct answers Analytical sensitivity
2 mL of a 1/20 dilution is to be made from a urine sample, using saline as a diluent.
How much urine is necessary to make this dilution? correct answers 100 uL
, Control of the diet in the population that you have selected for reference range interval
study is considered what type of quality control? correct answers pre-analytic
Analytical accuracy is measured correct answers By comparing sample results to those
obtained using an established "reference method."
The 95% confidence limits for calcium in control sera are 9.2-10.2 mg/L. Calculate the
standard deviation. correct answers 0.25 mg/L
The coefficient of variation (CV%) is: correct answers The standard deviation
expressed in terms of the percentage of the average of the values used to calculate the
standard deviation
From these data from the comparison of 40 replicates of the same lot of quality control
material for glucose on two different instruments, what can be concluded about methods
A and B?
Method A: Mean 102 mg/dL, SD 5 mg/dL
Method B: Mean 105 mg/dL, SD 2 mg/dL correct answers Method B is more precise
than method A
A direct measure of an assay's accuracy is known as: correct answers Difference of
bias from a "true" or reference method value
What must be included on a Safety Data Sheet? correct answers Reagent disposal
procedures
An unassayed control for albumin was run 40 times over a two week period. The mean
value is calculated to be 38 g/L. What does the standard deviation have to be in order
for the overall precision of the assay to meet a 3% coefficient of variation goal? correct
answers 1 g/L
The Henderson-Hasselbalch equation describes what type of characteristic chemical
action? correct answers Dissociation
An important reducing sugar found in the human body that causes disease when in
increased (abnormal) concentration is: correct answers glucose
Describe optimal conditions for transport, handling, and storage of blood specimens for
clinical chemistry testing? correct answers Specimen brought to lab immediately,
permitted to clot, serum separated and tested as soon as possible
Diurnal variation is a term that refers to: correct answers Time of day of specimen
collection
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