MICR221 EXAM QUESTIONS WITH CERTIFIED ANSWERS
What are the two classes of transport proteins - Answer-B-barrel and a-helicle bundle
How do Amphiphatic Transport proteins get their name - Answer-They need to function in hydrophobic conditions (bilipid layer) and have a hydrophilic core for tr...
What are the two classes of transport proteins - Answer-B-barrel and a-helicle bundle
How do Amphiphatic Transport proteins get their name - Answer-They need to function
in hydrophobic conditions (bilipid layer) and have a hydrophilic core for transport..
What are the 3 main types of active transporters - Answer-- Major facilitator Superfamily
(MFS)
- ATP binding cassette (ABC) superfamily
- Group translocation (phosphotransferase system)
Key Features of the MFS active transport - Answer-They are secondary carriers which
means they require energy first to function.
3 subsections
- Uniporter: transports one molecule across
- Antiporter: Switches molecules from Periplasm to Cytoplasm
- Symporter: simultaneous transport of two in the same direction
Most of the time pmf is used
What is the Rocker Switch Movement? (use Lactose permease) - Answer-Without
lactose present, the Lactose Permease protein has a very high binding affinity. When
lactose does bind to the Lactose permease transporter conformational change occurs
and the sugar is released on the other side of the membrane. The Proton causes a pmf
force that causes conformational change thus the "rocking" movement.
Key features of the ABC active transports - Answer-Multi-subunit transporters that
consist of two proteins. The periplasmic binding protein, binds and delivers solutes to
the membrane-spanning transporter, where ATP is hydrolysed to actively transport the
solute.
Key features of the Group Translocation active transporters. - Answer-Collection of
phosphate transfers that are used to modify and trap solutes inside the cell. Uses
energy from phosphate to power the tranport.
Two Phases of Glycolysis - Answer-energy investment phase and energy payoff phase
energy investment phase of glycolysis - Answer-2 ATP are invested to make the
intermediate glucose molecule less stable (6C ring broken into 2 3C chains)
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