BCH210 CLASS 6 EXAM QUESTIONS AND ANSWERS ALL CORRECT
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Module
BCH210
Institution
BCH210
BCH210 CLASS 6 EXAM QUESTIONS AND ANSWERS ALL CORRECT
The...on N gives peptide a.......bond character due to....., preventing....of the peptide bond - Answer-- lone pair of e
- partial double
- resonance
- rotation
Peptide bonds are....but...... The first feature contributes to the peptid...
BCH210 CLASS 6 EXAM QUESTIONS
AND ANSWERS ALL CORRECT
The...on N gives peptide a.......bond character due to....., preventing....of the peptide
bond - Answer-- lone pair of e
- partial double
- resonance
- rotation
Peptide bonds are....but...... The first feature contributes to the peptide bond by
allowing......., through the....... - Answer-- polar
- uncharged
- resonance
- breaking of the C=O bond
The plane of the peptide bond is always in the....... - Answer-same
organization/structure
While the peptide (also known as.....) bonds are planar (........), rotation is allowed
around the bonds linking the......(....) and ......(....) to the....... - Answer-- omega (w)
- all atoms on same plane
- amide (phi, 𝜙 )
- carbonyl (psi, Ѱ )
- alpha Carbon
Rotations around the......allows the polypeptide chain to.....Therefore, these two bonds
dictate path of....... - Answer-- phi + psI bonds
- twist up and form > compact structures (PROTEIN FOLDING)
- path of backbone
There are certain....of rotation allowed (can generate the..... plot) , ranging from....to.... -
Answer-- angles
- Ramanchandran
- -180 to +180 (????)
There are only certain angles allowed in polypeptide bond rotations (some are not.....)
because it can create....The preferred configuration is..... to.......because a lot of our
side chains are very......that's better to be.....from each other (gives you a more......) -
Answer-- permitted
- steric clashes
- trans
The...configuration can be allowed if the....want to interact - Answer-- cis
- two side chains
Which of the following AAs have the biggest impact on the path of the polypeptide
backbone?
A. G
B. H
C. P
D. W - Answer-Answer: C - proline
N involved in a ring -> phi bond is fixed, can NOT rotate and can only adopt one angle
(psi bond can though)
-> restrict kind of structures present
-> help protein structure fold
alpha helix have..pointing out to the....., and forms when...... - Answer-- side chains
- outside of helix (green bulbs on slide 10)
- peptide bonds have ability to H-bond w/ each other
alpha helix forms...... b/w......(example) - Answer-- INTRASTRAND H-bond
- O in backbone C=O of one AA (i) and H in H-N groups of another AA (i+4)
- ex: C1 H-bonds w/ C5
Alpha helix is formed because there are a lot of.....down the....of the helix,
creating..which forms a..... - Answer-- H-bonds buried
- center
- turns
- alpha helix
Figure C (slide 10): looking from the....all H-bonds......., protect your........
Figure D (slide 10):.....model, there's NO.....in the middle, there are....that are.....at the
center - Answer-- top
- hidden in the middle
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