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NUR 242 EXAM #2 QUESTIONS WITH COMPLETE SOLUTIONS
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NUR 242 EXAM #2 QUESTIONS WITH COMPLETE SOLUTIONS
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NUR 242 EXAM ONE QUESTIONS WITHCOMPLETE SOLUTIONS
Whatdisdpharmacology?d-dastudydofddrugsdthatdalterdfunctionsdofdlivingdorganisms
whatdisdpharmacokinetics?d-
dathedstudydofdhowdtheddrugsdmovedwithindthedbodydtodreachdsitesdofdaction,dmetabolism,da
nddexcretion
Whatdisdabsorption?d-
dathedprocessdthatdoccursdfromdthedtimedtheddrugdentersdthedbloodstream. dOnsetdofddrugdac
tiondisddetermineddbydrate.
Whatdfactorsdaffectdratedanddextentdofddrugdabsorption?dSATAd-dadosage,dform,droute
admindsitedblooddflow,dGIdfunctiond
presencedofdfood,dotherddrugs
Whatdisddistribution?d-datransportdofddrugsdindthedbody
Whatdcarriesddrugsdanddwheredto?d-
dablooddanddtissuedfluidsdtodactiondsites,dmetabolismdsites,dexcretiondsites
Whatdaffectsddistribution?d-daproteindbinding:ddrugsdbinddtodactdasdcarriers
blood-braindbarrier:dextremelydsmalldtodcross
pregnancyd-dplacenta
lactationd-dmanyddrugsdenterdthedbreastdmilk
whatdisdmetabolism?d-dathedwaydtheddrugsdaredinactivateddbydthedbodyd(cytochromedP-
450denzymedpathway)
whatdareddrugsdchangeddtodwhendmetabolized?d-dainactivedmetabolites
activedmetabolites
proddrugsd-ddrugsdthatdaredinactiveduntildmetabolized
wheredareddrugdmetabolizingdenzymesdlocatedd-
dakidney,dliver,dRBCs,dplasma,dlungs,dGIdmucosa
, Whatdaredfactorsdthatdaffectdmetabolism?d-daenzymedinductiond-
dchronicdadministrationdpromotesdthedliverdtodproducedlargerdamountsdofdthedenzymedandda
cceleratesdmetabolism
enzymedinhibitiondthatdoccursdwhendtwoddrugsdaredbeingdgivendatdthedsamedtimedthatdutiliz
edthedsamedenzyme
whatdisdexcretind-daeliminationdfromdthedbody
whatdisdthedmargindofdsafetydfordaddrug?d-datherapeuticdindexdofdtheddrug
whatdisdrequireddfordexcretion?d-
daadequatedfunctiondofdthedcirculatorydsystem,dkidneysdbowel,dlungs,danddskin
whatdisdpolypharmacy?d-
datakingdmultipleddrugs;dputsdindividualsdatdriskdforddrugdinteractions
whatddoesditdmakedsomeonedmoredsusceptibledtodifdthey'red85dwithdkidneydproblems?d-
dadrugdtoxicity
whatdisdaddrugsd"halfdlife"d-
dathedtimeditdtakesdfodhalfdofdtheddrugdtodbedeliminateddfromdthedbody
whatdisdthedorder/sequencedofdpharmacokinetics?d-
daabsorption,ddistribution, dmetabolism,dexcretion
whatdorganddoesdadlotdofdmetabolizing?d-dakidney
whatdisdadscheduledIddrug?d-
dahasdnodacceptabledmedicalduse,dhighdpotentialdfordabused(i.e.dheroine,dLSD)
whatdisdadscheduledIIddrug?d-
danarcoticsdordstimulants dwithdhighdpotentialdfordabused(oxycodone,dmorphine,dadderall)
whatdisdadscheduledIIIddrug?d-
dalessdpotentialdfordabused(Tylenoldwithdcodeine,danabolicdsteroids)
whatdisdadscheduledIVddrug?d-dahasdlowerdpotentialdfordabused(versed,dXanax)
whatdisdadscheduledVddrug?d-dapreparationsdthatdhavedlimiteddquantitiesdofdnarcotics
whatdisdsynergism?d-
datwoddrugsdwithddifferentdactionsdcreatedadgreaterdeffectd(i.e.dacetaminophend+dopioids)
Whatdaredthedpatient-relateddvariables?dSATAd-daage,dbodydweight
genetics,dethnicity,dgender
pharmacogeneticsd(studydofdgeneticddrugdresponse)
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