What are the major antibiotic drug classes - ANSWER Beta-lactams: penicillins
Beta-lactams: Cephalosporins
fluoroquinolones
tetracyclines and macrolides
sulfonamides, trimethoprim, &nitrofurantoin
which antibiotics are preferred for immunocompromised patients: bactericidal or bacteriostatic...
, bacteriostatic antibiotics - ANSWER Antibiotics that do not actually kill bacteria but rather inhibit
bacterial proliferation while the hosts immune system does the killing
which antibiotics increase the risk of antibiotic resistance: narrow or broad spectrum and why -
ANSWER Broad spectrum because they kill more competing organisms than narrow spectrum drugs
is narrow or broad spectrum antibiotics preferred - ANSWER narrow is preferred when possible.
broad spectrum only used when pathogen is unknown or when multiple types of bacteria is
suspected
Bactericidal drugs - ANSWER Aminoglycosides
Beta-lactams
fluoroquinolones
Metronidazole
Vancomycin
streptogramins
most antimycobacterial agents (rifampin, isoniazid, streptomycin, etc)
penicillins primarily excreted how - ANSWER in urine
what needs to be monitored when giving penicillins - ANSWER renal function
what happens if renal insufficiency occurs while giving penicillins - ANSWER prolonged half-life
leading to toxicity
Penicillin distribution - ANSWER -Well distributed to most body tissues
-Penetration to CSF and eye tissues poor in absence of inflammation
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