TEST BANK FOR CLAYTON’S BASIC PHARMACOLOGY FOR NURSES 18TH EDITION BY WILLIHNGANZ
Test Bank for Clayton's Basic Pharmacology for Nurses, 18th Edition by Willihnganz, 9780323550611, Covering Chapters 1-48 | Includes Rationales| Latest
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BASIC PHARMACOLOGY FOR CAREGIVERS 19TH EDITION
BASIC PHARMACOLOGY FOR CAREGIVERS 19TH EDITION
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TEST BANK FOR CLAYTON’S BASIC PHARMACOLOGY
FOR CAREGIVERS 20 TH EDITION BY MICHELLE J.
WILLIHNGANZ, SAMUEL L. GUREVITZ, BRUCE CLAYTON
CHAPTER 1-48
,Chapter 01:Drug Definitions, Standards, And Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Caregivers, 20th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and
Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
RIGHT SELECT:->>C
Rationale :>>>The official name is the name under which a
drug is listed by the FDA. The brand name, or trademark, is
the name given to a drug by its manufacturer. The
nonproprietary, or generic, name is provided by the United
States Adopted Names Council
DIF: Cognitive Level: Knowledge REF: p. 9
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
Environment TOP: Nursing Process Step: Assessment CON:
Client Education
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
RIGHT SELECT:->>C
Rationale :>>>United States Pharmacopoeia/National Formulary contains information specific to
nutritional supplements. USP Dictionary of USAN & International Drug Names is a compilation of
drug names, pronunciation guide, and possible future FDA approved drugs; it does not include
nutritional supplements. Natural Medicines Comprehensive Database contains
evidence-based information on herbal medicines and herbal combination products; it does not
include information specific to nutritional supplements. Drug Interaction Facts contains
comprehensive information on drug interaction facts; it does not include nutritional
supplements.
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
a. Drug Facts and Comparisons
, 3
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale—The Complete Drug Reference
RIGHT SELECT:->>A
Rationale :>>>Drug Facts and Comparisons contains drug monographs that
describe all drugs in a therapeutic class. Monographs are formatted as tables to allow
comparison of similar products, brand names, manufacturers, cost indices, and
available dosage forms Online version is available.
4. Which drug reference contains monographs about virtually every single-entity drug available
in the United States and describes therapeutic uses of drugs, including approved and
unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
RIGHT SELECT:->>B
Rationale :>>>AHFS Drug Information contains monographs about virtually every single-
entity drug available in the United States and describes therapeutic uses of drugs, including
approved and unapproved uses.
5. Which online drug reference makes available to healthcare providers and the public a
standard, comprehensive, up-to-date look up and downloadable resource about medicines?
a. American Drug Index
b. American Hospice Formulary
c. DailyMed
d. Drug Reference
RIGHT SELECT:->>C
Rationale :>>>DailyMed makes available to healthcare providers and the public a standard,
comprehensive, up-to-date look up and downloadable resource about medicines. The
American Drug Index is not appropriate for client use. The American Hospice Formulary is
not appropriate for client use. The drug reference is not appropriate for client use.
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
, 4
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
RIGHT SELECT:->>A
Rationale :>>>The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to
determine the safety of all drugs before marketing. Later amendments and acts helped tighten
FDA control and ensure drug safety. The Durham Humphrey Amendment defines the kinds
of drugs that cannot be used safely without medical supervision and restricts their sale to
prescription by a licensed practitioner. The Controlled Substances Act addresses only
controlled substances and their categorization. The Kefauver Harris Drug Amendment
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove to
the FDA the effectiveness of their products before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Client Education | Evidence | Health Care Law
7. Which classification does meperidine (Demerol) fall under?
a. I
b. II
c. III
d. IV
RIGHT SELECT:->>B
Rationale :>>>Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse
and may lead to severe psychological and physical dependence. Schedule I drugs have high
potential for abuse and no recognized medical use. Schedule III drugs have some potential for
abuse. Use may lead to low to moderate physical dependence or high psychological
dependence. Schedule IV drugs have low potential for abuse. Use may lead to limited
physical or psychological dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Client Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and approval for an outbreak
of smallpox?
a. List smallpox as a health orphan illness.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
RIGHT SELECT:->>D
Rationale :>>>Once the Investigational New Drug Application has been approved, the drug
can receive highest priority within the agency, which is called fast tracking. A smallpox
outbreak would become a priority concern in the world. Orphan illnesss are not researched in
a priority manner. Preclinical research is not omitted. Extending any phase of the research
would mean a longer time to develop a vaccine. The FDA must ensure that all phases of the
preclinical and clinical research phase have been completed in a safe manner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
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