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NSG 251 FINAL EXAM QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
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NSG 251 FINAL EXAM QUESTIONS AND ANSWERS WITH SOLUTIONS 2024
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NSG 251 FINAL EXAM QUESTIONS ANDANSWERS WITH SOLUTIONS 2024
RankRspeedRofRabsorption:RPo,RIM,RIVR-RANSWERRPoRslowest,RthenRIM,RIVRfastest
DescribeRdrugRdistributionRinRrelationRtoRproteinRbindingR-RANSWERRProteinRbinding-
RMostRdrugsRformRaRcompoundRandRbindRwithRplasmaRproteins.RDrugRmoleculesRboundRtoRplasmaRprotein
sRareRpharmacologicallyRinactive.ROnlyRtheRfreeRorRunboundRportionsRofRtheRdrugRactsRonRtheRcells.RProtei
nRbindingRallowsRforRsomeRofRtheRdrugRtoRbeRstoredRandRothersRtoRbeRreleasedRasRneeded.RThisRgivesRtheRc
onstantRbloodRlevelRandRdecreasedRriskRforRtoxicity.R
HighRbinding=highRdurationRofRaction.
FirstRpassReffectR-
RANSWERRaRphenomenonRofRdrugRmetabolismRwherebyRtheRconcentrationRofRaRdrugRisRgreatlyRreducedRbe
foreRitRreachesRtheRsystemicRcirculation.RItRisRtheRfractionRofRdrugRlostRduringRtheRprocessRofRabsorptionRw
hichRisRgenerallyRrelatedRtoRtheRliverRandRgutRwall.
DoesRliverRfailureRaffectRdrugRmetabolism?R-RANSWERRLiverRfailureRdoesRaffectRmetabolismRofRdrugs
DrugRexcretionR-RANSWERReliminationRofRdrugRfromRtheRbodyRbyRkidneysRorRbowel
WhatRareRtheRnurse'sRresponsibilitiesRforRdrugRadministration?R-
RANSWERRRightRdrug,Rdose,Rroute,Rpatient,Rtime,RdocumentationR(responseRorRrefusal),Rreason
PrototypeR-RANSWERRTheR"leadRagent"RinRtheRdrugRclass.REx.RmetoprololRisRprototypeRofRbeta-1Rblockers
FederalRFoodRandRDrugRActR-RANSWERRaccurateRlabeling
Durham-HumphreyRAmendmentR-
RANSWERRdesignatedRdrugsRthatRmustRbeRprescribedRbyRaRphysicianRandRadministeredRbyRaRpharmacist
TheRcomprehensiveRabuseRandRcontrolRactR-RANSWERRregulatedRnarcoticsRandRcategorized
,OrphanRDrugRActR-
RANSWERRdecreasedRtaxesRandRcompetitionRthatRaffectedRdrugsRassociatedRwithRrareRdiseases
DrugRApprovalR-
RANSWERRFDARregulatesRtheRprocessRbyRwhichRdrugsRareRresearchedRandRreleasedRtoRpopulation.
ClinicalRtrialRphasesR-RANSWERRPhaseRI-aRfewRdosesRareRgivenRtoRhealthyRvolunteers
PhaseRII-smallRdosesRareRgivenRtoRpeopleRwithRdisease
PhaseRIII-largerRandRmoreRrepresentativeRgroupRofRpatients--RdrugRandRplaceboRgroups
PhaseRIV-allowsRdrugRtoRbeRmarketed,RcompanyRhasRtoRmonitorRandRreportRadverseReffects
GramRpositiveRantibioticsR-RANSWERRPenicillian,RCephalosporins
GramRnegativeRantibioticsR-RANSWERRAminoglycosides
BroadRspectrumRantibioticsR-RANSWERRCephalosporins,RCarbapenems,RTetracyclines
SulfonamideRcontraindicationsR-RANSWERRPatientsRwithRaRsulfaRallergy
SulfonamidesRusesR-RANSWERRInhibitRbacteria;RUTI,R2ndRandR3rdRdegreeRburns
SulfonamideRdrugsR-RANSWERRtrimethprim/sulfamethoxazoleR(Bactrim),R
silverRsulfadiazineR(Silvadene)Rointment
SulfonamideRadverseR-RANSWERRN/V/D,RallergicRreaction
PenicillinRusesR-
RANSWERRWorksRonRGram+Rbacteria;Rstrep,RpneumococcalRpneumonia,Rendocarditis,Rmeningitis,RpreventR
endocarditis
,PenicillinRadverseR-RANSWERRrash,Ranaphylaxis,Rneurotoxicity,RGIRsymptoms
PenicillinRnursingR-RANSWERRwatchRforRAllergicRreaction(rash),RtakeRonRanREmptyRstomach
PenicillinRdrugsR-RANSWERRpenicillinRG
Amoxicillin
Ampicillin
tazobactamR(Zosyn)
CephalosporinRusesR-
RANSWERRBactericidal(killsRbacteria),RInhibitRcellRwallRsynthesis,RBroadRspectrum,RGramR+R/-
(dependingRonRgeneration)R5RgenerationsRofRdrugs(RasRtheRgoRupRinRnumberRtheyRbecomeRmoreRGram-
Reffective)
--surgicalRprophylaxis-RSCIP,RUTI,RPCNRresistantRgonorrhea
CephalosporinRadverseR-RANSWERRcrossRsensitivityRw/RPCN,RGIRsymptoms
-->TakeRmostRw/Rfood
CephalosporinRdrugsR+RusesRforRspecificRonesR-RANSWERRcefazolinR(Kefzol)R-RIV,R1stRgeneration,R
cephalexinR(Keflex)Rpo
cefuroximeR(Zinacef),R2ndRgeneration
ceftriaxoneR(Rocephin),R3rdRgeneration-RghonorrheaRuse
cefepimeR(Maxipime)R4thRgeneration
ceftarolineR(Teflaro)R5thRgeneration:RusedRforRMRSARandRGramR(-)Rinfections
CarbapenemRusesR-RANSWERRBroadRspectrum,Rbactericidal,RInhibitRcellRwallRsynthesis
--RusedRinRstaph,RE.RcoliR(complicatedRbodyRcavity/connectiveRtissueRinfections)
, CarbapenemRadverseR-
RANSWERRDrugRinducedRseizures(RinRchildren,Rrare),RrelatedRtoRPCNRsoRcheckRallergies
CarbapenemRdrugR-RANSWERRimipenemRcilastatinR(Primaxin),RIV
MacrolidesRusesR-RANSWERRBacteriostatic,RbactericidalRinRlargeRdoses,RInhibitRproteinRsynthesis
--RusedRinRstaph,Rstrep,RgonorrheaRandRchlamydia,RURI
MacrolidesRadverseR-RANSWERRGI,RN/V,RGIRbleed
MacrolidesRdrugsR-RANSWERRerythromycinR(E-mycin)
azithromycinR(Zithromax)
TetracyclineRusesR-RANSWERRBroadRspectrum,Rbacteriostatic,RGramR+/-Rorganisms
--RUsedRforRHRpylori,Rchlamydia,RPID,Racne,Rsyphilis
TetracyclineRcontraR-RANSWERRrenalRfailure,RnoRuseRchildrenR<8yrs,Rpregnancy
TetracyclineRadverseR-RANSWERRDiscolorationRofRpermanentRteeth,RGI,Rrashes
TetracyclineRdrugsR-RANSWERRdoxycyclineR(Vibramycin)
**increaseRresistanceRofRthisRdrugRsoRdecreasedRuse
**relatedRtoRPCNRsoRwatchRforRallergicRreactions
AminoglycosideRusesR-RANSWERRBactericidals,RInhibitRproteinRsynthesis
--usedRforRseriousRgramRneg.Rinfections,RpreoperativelyRforRGI/GURtractRsurgeries
AminoglycosideRcontraR-RANSWERRpregnancy
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