Test Bank for Abrams' Clinical Drug Therapy: Rationales for
Nursing Practice 13th Edition by Frandsen and Pennington
,Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A lady diagnosed with obsessive–compulsive disorder has been prescribed oral
paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
CORRECT ANSWER: B
Elaboration: Medications that produce systemic effects are taken into the body, circulated
through the bloodstream to their sites of action in various body tissues, and eventually
eliminated from the body. Curative agents are given to cure a disease process. In this case,
paroxetine hydrochloride will control the symptoms but not cure the disorder. Medications
with local effects, such as sunscreen and local anesthetics, act mainly at the site of
application. Paroxetine hydrochloride is not administered parenterally. Parenteral agents are
administered subcutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheG
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SoBdOifOieSd.TWhaOt Mi s another name for this type of
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medication?
A. Synthetic medication
B. Semisynthetic medication
C. Biotechnology medication
D. Prototype medication
CORRECT ANSWER: B
Elaboration: Semisynthetic medications (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic medications are more standardized
in their chemical characteristics, more consistent in their effects, and less likely to produce
allergic reactions. Biotechnology medications involve manipulating DNA and RNA and
recombining genes into hybrid molecules that can be inserted into living organisms.
Prototype medications are the first medication of a particular group to be developed.
PTS: 1 REF: p. 3, Medication Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
C. Anti-inflammatory
D. Antihypertensive
CORRECT ANSWER: A
Elaboration: Medications are classified according to their effects on particular body
, systems, their therapeutic uses, and their chemical characteristics. Morphine is classified as
a central nervous system depressant and will produce this effect in the client. A central
nervous system stimulant increases attention and raises mood. An anti-inflammatory agent
decreases inflammation at the site of tissue or joint inflammation. An antihypertensive agent
reduces blood pressure.
PTS: 1 REF: p. 3, Medication Classifications and
Prototypes OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to which
medication group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
CORRECT ANSWER: C
Elaboration: The generic namGeRoA fteDnEiS
ndBicOaO
teS
sTth.e CdrOug group (e.g., medications with
generic names ending in “cillin” are penicillins). Selective serotonin reuptake inhibitors are
medications
that have antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics
are medications that increase urine output; diuretic is a broad classification, not a generic
name. ACE inhibitor is the broad classification for the angiotensin receptor blockers, not the
generic name.
PTS: 1 REF: p. 3, Medication Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Medication
Administration CORRECT
ANSWER: D
, Elaboration: The Food and Medication Administration approves medications for over-the-
counter availability, including the transfer of medications from prescription to OTC status,
and may require clinical trials to determine the safety and effectiveness of OTC use. The
Public Health Service is regulated by the state to maintain the health of individual citizens
of the state. The Federal Trade Commission regulates imports and exports throughout the
nation. The Occupational Safety and Health Administration regulates safety within the
workplace.
PTS: 1 REF: p. 4, Prescription and Nonprescription
Medications OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Medication, and Cosmetic Act of 1938
B. The Comprehensive Medication Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
CORRECT ANSWER: B
Elaboration: The Comprehensive Medication Abuse Prevention and Control Act regulates
the manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
anabolic steroids. The Food, Medication, and Cosmetic Act of 1938 revised and broadened
FDA powers and responsibilities, giving the FDA control over medication safety. The
Harrison Narcotic Act restricted the importation, manufacture, sale, and use of opium,
cocaine, marijuana, and other medications that the act d e f i Gn eRd AaDs E
naSrcBoO
tiO
csS
.TTh.eCSOhM
erley
Amendment of 1912 prohibited fraudulent claims of medication effectiveness.
PTS: 1 REF: p. 4, Prescription and Nonprescription
Medications OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nursing practitioner is responsible for maintaining an accurate count and record of the
controlled substances on the nursing division. This nursing action is regulated by which
U.S. law or agency?
A. The Food, Medication, and Cosmetic Act of 1938
B. The Public Health Service
C. The Medication Enforcement Administration
D. The Sherley Amendment
CORRECT ANSWER: C
