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Exam (elaborations)

PHARMACOLOGY MSN 571

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PHARMACOLOGY MSN 571

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  • September 18, 2024
  • 5
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
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PHARMACOLOGY MSN 571 NEWEST ACTUAL EXAM
COMPLETE 140 QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS) |ALREADY GRADED A+
Prescriptive authority - ANSWER: legal authority granted to advanced practice nurses
to prescribe medication; DETERMINED BY STATE LAW

Rational Drug Selection - ANSWER: based on individual patient and addresses
disease specific information: ONLY A GUIDELINE

Drug Selection - ANSWER: includes analysis of cost, guidelines, avaibalbility,
interactions, side effects, allergies, hepatic and renal function, need for monitoring,
special precautions i.e elderly

medication education basic components - ANSWER: medication name
purpose
dosing regimen
administration
adverse effects
any storage needs
associated labs testing
food & drug interactions
duration of therapy

medication adherence - ANSWER: barriers to adherence=
forgetfulness
lack of planning
cost
dissatisfaction
altered dosing

Phamacokinetics - ANSWER: study of drug movement throughout body

principles of pharmacokinetics - ANSWER: absorption
distribution
metabolism
excretion

Passage of drugs across membranes - ANSWER: - channels and pores
- transport systems (P-glycoprotein)
- direct penetration of the membrane

Absorption of drugs - ANSWER: Transfer of drugs from site of administration across
cell membrane into the blood stream

, factors that affect absorption of drugs - ANSWER: rate of dissolution- how easy
dissolves
surface area- >surface area moves faster
blood flow- >blood flow moves faster
lipid solubility - lipid easily cross membrane
ph partitioning -

Distribution of drugs - ANSWER: movement of drugs from systemic circulation to site
of drug action

factors that determine drug flow - ANSWER: blood flow to tissues
ability to exit vascular system
ability to enter cell

Drug ability to exit vascular system - ANSWER: capillary bed- typical
blood brain barreier
placenta drug transfer
protein binding - albumin

drug ability to enter cell - ANSWER: binds with receptors on external surface of cell
membrane

drug metabolism - ANSWER: the enzymatic biotransformation of a drug structure
most occur in liver by P450 system

first pass effect - ANSWER: rapid hepatic inactivation of drug on its first pass through
liver

drug excretion - ANSWER: elimination of a drug from the body

Drug Excretion Routes - ANSWER: renal
breast milk
bile
lungs
sweat
saliva

therapeutic drug range - ANSWER: range of drug between minimum effective dose
and toxic dose. larger index - safer dose smaller index- harmful dose

drug half life - ANSWER: the time required for the amount of drug in the body to
decrease by 50%

Phamacodynamics - ANSWER: biochemical and physiological effects of drugs on body

dose-response relationship - ANSWER: the relationship between the size of an
administered dose and the intensity it produces

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