NPLEX II- Dermatology Questions and Correct Answers | Latest Update
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Module
NPLEX
Institution
NPLEX
What causes actnic keratosis? is it malignant?
-:- pre-malignant epidermal lesion caused by excessive chronic sunlight
exposure.
Pre-cursor to squamous cell carcinoma (SCC) but only 2-5% actually become SCC
Clinical features of basal cell carcinoma
-:- pearl papule with telangiectatic (spid...
Describe the typical initial presentation of squamous cell carcinoma (including m/location).
✓ -:- Initial presentation: hx of non -healing ulcer or abnormal growth from
sun exposed area
70% occur on head & neck (often involving lower lip)
DDx btw bullous pemphigold and vulgaris pemphigus
✓ -:- Bullous- IgG antibodies against dermal epidermal basement
membrane proteins that lead to subepidermal bullae; don't easily rupture
Pemphigus Vulgaris- potentially FATAL autoimmune dz; bullae rupture resulting in
secondary bacterial infections, septicemia, and fluid loss
2|P a g e | G r a d e A + | 2 0 2 0 2 5
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