Exam (elaborations)
NR 566 WEEK 1 QUESTIONS AND ANSWERS
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NR 566 WEEK 1 QUESTIONS AND ANSWERS
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Name: Score:131 Multiple choice questions
Term 1 of 131
Penicillin distribution
Ampcillin/sulbactam (unasyn)
amoxicillin/clavulanate (augmentin)
piperacillin/tazobactam (zosyn)
check for interactions of other drugs the patient is taking as tetracycline interacts with
many drugs including digoxin
alternative to penicillin G in pts with penicillin allergy
treatment of choice for diphtheria
-Well distributed to most body tissues
-Penetration to CSF and eye tissues poor in absence of inflammation
Term 2 of 131
fluoroquinolone black box warning
increased risk of gastrointestinal bleeding
enhanced effectiveness of other antibiotics
tendon rupture and exacerbation of muscle weakness in patients with myasthenia gravis
no significant risks associated with their use
Term 3 of 131
2nd-5th generations cephalosporins susceptible pathogens
broad spectrum gram positive and gram negative bacteri
only anaerobic bacteria and certain protozoa
narrow spectrum targeting only gram positive bacteria
specific strains of viruses and fungi
,Term 4 of 131
4th generation cephalosporins
Ceftaroline (teflaro)
Cephalexin (keflex)
Cefepime (Maxipime)
Ceftriaxone (rocephin)
Term 5 of 131
how do carbapenems effect emergence of resistance
teeth- yellow/brown discoloration, hypoplasia of enamel
bones-if taken while pregnant will suppress growth of long bones of infant
IV due to poor GI absorption
except for CDIFF infections which it can be given orally
carbapenems are extremely broad-spectrum and effective at killing both gram positive
and gram negative bacilli which can lead to emergence of resistance which is actually a
global healthcare problem that is being talked about
reserve prescribing to only patients who cannot be treated with a more narrow-
spectrum agent
,Term 6 of 131
if a patient has a severe allergy to penicillins what is an appropriate drug alternative
Naficillin
oxacillin
dicloxacillin
Piperacillin
Imipenem
meropenem
ertapenem
doripenem
NOT CEPHALOSPORINS
vancomycin
erythromycin
clindamycin
Term 7 of 131
Vancomycin MOA
skin and soft tissue infection
inhibits cell wall synthesis
-bacteriocidal
inhibits protein synthesis, bacteriostatic
inhibit cell wall synthesis; bactericidal
, Term 8 of 131
bacteriostatic drugs
Azithromycin
Clarithromycin
Erythromycin (oldest)
antibiotics that do not actually kill bacteria but rather inhibit bacterial proliferation while
the hosts immune system does the killing
piperacillin
clindamycin
macrolides
sulfonamides
tetracyclines
Term 9 of 131
Penicillin/Beta lactamase combinations
Inhibit protein synthesis (bacteriostatic)
Ceftaroline (teflaro)
Ampcillin/sulbactam (unasyn)
amoxicillin/clavulanate (augmentin)
piperacillin/tazobactam (zosyn)
calcium supplements
milk products
iron supplements
magnesium laxatives
most anatacids
Term 10 of 131
what is the empiric therapy of choice for CAP
kill bacteria without harming host tissue
combinations beta-lactam plus macrolide
cephalosporins
kill bacteria without harming host tissue
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