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Musculoskeletal - Adv Pharm - NURS8024 Questions and Answers
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Musculoskeletal - Adv Pharm - NURS8024 Questions andAnswers
What is the name for the urate crystals in joint? Correct Ans-Tophi
In Gout crystals present as tophaceous gout or urate nephropathy if crystallization is in the
_________________ ____________. Correct Ans-Renal Medulla
What is the first line drug choice for Gout? Correct Ans-Colchicine
Treatment of hyperuricemia _______________ acute attack is over. Correct Ans-AFTER
What is the MOA for Colchicine? Correct Ans-Decreases in Uric Acid response
T/F : Colchicine works as an analgesic as well. Correct Ans-False - NEED TO RX an NSAID too
An important patient teaching to a patient prescribed Colchicine includes: Correct Ans-
Avoid Grapefruit Juice &
Some ANTBXs
What would you monitor for 1st time users of Colchicine? Correct Ans-Vitamin B12 and
LFTs
, Musculoskeletal - Adv Pharm - NURS8024 Questions and
Answers
What is the MOA for Xanthine Oxidase Inhibitors? Correct Ans-Decrease uric acid
production by inhibiting xanthine oxidase
Name the two gout medications that fall within the class of Xanthine Oxidase inhibitors?
Correct Ans-Allopurinol and Febuxostat
All except _________ selective agents and _______________ inhibit platelet aggregation.
Correct Ans-COX-2 ; Nonacetylated Salicylate
MOA for COX-2 Selective Inhibitors (Coxibs) Correct Ans-Inhibits prostaglandin synthesis at
sites with inflammation without affecting COX-1 (GI, Kidney, Plus)
Name the four MOA of Aspirine: Correct Ans-1. Anti-Inflammatory Effects (Prostaglandin,
thromboxjnes, bradykinin and histamine)
2. Analgesic Effect
3. Antipyretic Effect
4. Antiplatelet Effect
ASA can cause _______________ of _____________ for the _______________ of the platelet.
Correct Ans-Inactivation ; COX-1 ; Life
First line of treatment for MSK Pain? Correct Ans-Rest
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