Exam (elaborations)
NURS8024 Pharm Exam 3 (antimicrobial part 1)- Questions and Answers
- Module
- Institution
NURS8024 Pharm Exam 3 (antimicrobial part 1)- Questions and Answers
[Show more]
Seller
Follow
GOLDTUTORS
Reviews received
Content preview
NURS8024 Pharm Exam 3 (antimicrobial part 1)-Questions and Answers
Minimum inhibitory concentration (MIC) Correct Ans-Estimate of the drug sensitivity of a
pathogen for comparison with anticipated levels in blood or tissues
Lowest concentration of antibiotic inhibiting bacterial growth
Effective antimicrobial Tx should have antibiotic concentration> MIC
Post-antibiotic effect (PAE) Correct Ans-Antibacterial effect that persists after drug
concentration falls below the minimum inhibitory concentration (MIC)
Susceptibility testing Correct Ans-Culture indicates the sensitivity of the isolated pathogen
to specific antimicrobial drugs
Predicts MIC
- estimate of the drug sensitivity of pathogen compared to the anticipated levels in the blood
or tissues
BacterioSTATIC antimicrobial Correct Ans-Chloramphenicol,Clindamycin, Ethambutol,
Macrolides, Nitrofurantoin, Novobiocin, Oxazolidinones, Sulfonamides, Tetracyclines,
Tigercycline, Trimethoprim
Inhibits growth and replication of bacteria
, NURS8024 Pharm Exam 3 (antimicrobial part 1)-
Questions and Answers
Limits spread of infection-Enables immune system to attack pathogen
BacterialCIDAL antimicrobial Correct Ans-Aminoglycosides, Bacitracin, Beta- Lactam
antibiotics, Isoniazid, Ketolides, Ketolides, Metronidazole, Polymyxins, Pyrazinmide,
Quinolones, Rifampin, Streptogramins
Kills bacteria
Total number of viable organisms decreases
Concentration-dependent killing Correct Ans-Increased kill rate w/ increased
concentration
Often allows daily dosing to achieve efficacy w/ increased peak levels
Aminoglycosides & quinolones
Time-dependent killing Correct Ans-bactericidal activity dependent on time serum
concentration, ↑ MBC predicts efficacy
AUC/MIC ratio
, NURS8024 Pharm Exam 3 (antimicrobial part 1)-
Questions and Answers
Needs more frequent dosing
β lactams, macrolides, vancomycin
Cell wall synthesis inhibitors Correct Ans-Beta-lactams
(PCN, cephalosporins, Vanco)
Gram-positive bacteria Correct Ans-Stain violet/purple
cocci-Streptococcus pygenes
rods- Clostridium perfringens
Gram-negative bacteria Correct Ans-Stain pink
Aerobes Correct Ans-require oxygen
most common cause of infection
obligate aerobes & others
Common gram positive aerobes Correct Ans-Staphylococci-resistance- Methiciliin resistant
staphylococcus aureus (MRSA_
Streptococci
Enterococcus-resistance-Vancomycin resistant enterococcus (VRE)
, NURS8024 Pharm Exam 3 (antimicrobial part 1)-
Questions and Answers
Common gram negative aerobes Correct Ans-Moraxella catarrhalis
neisseria gonorrhoeae
Haemophilius influenzae (HIB)
Space bugs Correct Ans-Hard to treat organisms
Serratia
Pseeudomonas aeriginosa
Acinetobacter helocobacter
Citrobacter
Enterobacter
Anaerobes Correct Ans-Thrive w/out oxygen
Virulence factors
Release exotoxins
Local microbiota enter previously sterile tissue
common anerobes Correct Ans-Clostridium perringes, difficile (C-diff)
Fusobacterium
Actinomyces (abdominal infections), bacteroides fragilis- anarobe most commonly isolated
from intraabdominal infections and bacteremia
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller GOLDTUTORS. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £16.36. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
67474 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now