8024 Pharmacology Test 2 Module 4 Part 1 & 2-
Questions and Answers
These drugs selectively inhibit NaCL reabsorption in the ascending loop of Henle Correct
Ans-Loop Diurectics
The Most Effective Diuretic Agents Correct Ans-Loop Diuretics
These drugs are used to decrease intravascular volume in heart failure, acute pulmonary
edema and acute hypercalcemia and hyperkalemia. Correct Ans-Loop Diuretics
Contraindications are possible allergic cross reactivity in pts sensitive to other sulfonamides.
Correct Ans-Loop Diuretics
Which loop Diuretics are Sulfonamides? Correct Ans-Furosemide
Bumetanide
Torsemide
What should you monitor for loop diuretics? Correct Ans-BP
Electrolytes = K+, Mg, Ca+
Daily wts
ADE of the drugs include: Hypotension, Hypokalemia, Hypomagnesaemia
Severe Hypovolemia
, 8024 Pharmacology Test 2 Module 4 Part 1 & 2-
Questions and Answers
Hyperuricemia
Aldosterone Antagonists are also known as what? Correct Ans-K+ Sparing Diuretics
Name 2 Aldosterone Antagonists? Correct Ans-Spironolactone
Eplerenone
Prevents K+ secretion by antagonizing the effects of aldosterone in collecting tubules.
Correct Ans-Mechanisms of K+ Sparing Diuretics
Reduce Na+ ABSORPTION in the collecting tubules and ducts
, 8024 Pharmacology Test 2 Module 4 Part 1 & 2-
Questions and Answers
Actions of aldosterone antagonists-dependent on renal prostaglandin production Correct
Ans-Mechanisms of K+ Sparing Diuretics
Agents that increase urine volume Correct Ans-Diuretics
Mechanisms of Diuretics Correct Ans-Multiple effects on renal physiology
Effect specific membrane transport proteins in renal tubular epithelial cells
Osmotic effects that prevent water reabsorption
Inhibit enzymes
Interfere with hormone receptors in renal epithelial cells
Synergistic with loop diuretics = marked diuresis Correct Ans-Thiazide Diuretics
Drugs that decrease BP initially by decreasing plasma volume and its long-term hemodynamic
effects are to decrease PVR Correct Ans-Thiazide Diuretics
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