PHCY 512 Exam 1 Questions with Correct
Answers
Pharmaceutics Correct Answer-Study of physical and chemical
properties of drugs related to dosage form design and manufacturing
Goals of drug delivery Correct Answer-Right amount of active
ingredient.
Right drug target.
Right amount of time.
Desired pharmacological outcome.
Biopharmaceutics Correct Answer-Applied science that examines the
relationship between:
- Physical and chemical properties of a drug in a dosage form
- Biological fate of a drug
- Observed biological response
A drug is: Correct Answer-A substance that is:
- Recognized by an official pharmacopeia or formulary
- Intended for use in the diagnosis, cure, mitigation, treatment or
prevention of disease
- Intended to affect the structure or any function of the body
- Intended for use as a component of medicine but not a device,
component, part or accessory of a device
,Which organization is responsible for maintaining the official
compendia for the US? Correct Answer-USP-NF
Excipients Correct Answer-Inactive ingredient, intended to furnish
pharmacological activity or other direct effect
Any component other than the API
Dosage Form Correct Answer-the physical manifestation containing the
active and inactive ingredients that delivers a dose of the drug product
Powders Correct Answer-Fine, solid particles, may be composed of only
the API or may be a mixture of active/inactive ingredients
Tablet Correct Answer-Compressible vehicle that is blended with the
medicinal agent, and if necessary a lubricant, disintegrant, and
compressed
Capsule Correct Answer-Gelatin shells filled with the ingredients that
make up an individual dose. May contain dry powders, semi-solids, or
liquids that (that don't dissolve gelatin)
Solution Correct Answer-Homogenous one-phase system composed of
2+ components, one of which is completely dissolved in the other and
dispersed throughout the solvent kin molecular or ionic sized particles
, Suspension Correct Answer-two-phase system consisting of finely
divided solid dispersed (suspended) in a liquid dispersing medium
Qualities of Ideal Dosage Form Correct Answer-One dose in a
manageable size unit
Palatable/comfortable
Stable
Convenient/easy to use
Release of Drug
Medication Adherence Correct Answer-the extent to which patients take
medications as prescribed by their health care providers
Reasons for poor adherence Correct Answer-Cost, memory, side effects,
lack of education, too many medications, misunderstanding instructions
Drug Disposition Correct Answer-What happens to a drug after it has
been administered
- Understood with LADME
LADME Correct Answer-Liberation - release of drug from dosage form
Absorption - drug uptake into the body
Distribution - drug circulation, entry into cells
Metabolism - enzymatic action on drug to more readily eliminable forms
Excretion - removal of a drug from the body
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