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NU 545 CH 9 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE

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NU 545 CH 9 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS LATEST UPDATE Hypersensitivity Altered immunologic response to an antigen that results in disease or damage to the host allergy Deleterious effects of hypersensitivity to environmental antigens Autoimmunity Disturbance in the im...

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  • October 10, 2024
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  • 2024/2025
  • Exam (elaborations)
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NU 545 CH 9 EXAM QUESTIONS AND ANSWERS

WITH COMPLETE SOLUTIONS LATEST UPDATE


Hypersensitivity


Altered immunologic response to an antigen that results in disease or damage to the host


allergy


Deleterious effects of hypersensitivity to environmental antigens


Autoimmunity


Disturbance in the immunologic tolerance of self-antigens


Alloimmunity


Immune reaction to tissues of another individual


immunologic homeostasis


steady state of tolerance to self-antigens or lack of immune reaction against environmental antigens


Anaphylaxis


a severe response to an allergen in which the symptoms develop quickly, and without help, the patient

can die within a few minutes.


Type I IgE-Mediated Hypersensitivity


Mediated by antigen-specfic IgE and the products of tissue mast cells

, Cytotropic antibody


Antibody that binds to mast cells


Reagin


skin-sensitizing antibody


Type II: Tissue-specific Hypersensitivity Reactions


Characterized by a specific cell or tissue being the target of an immune response


Tissue specific antigens


Expressed on the plasma membranes in only certain cells in specific tissues


5 ways type II hypersensitivity reactions can affect cells


1)cell can be destroyed by antibody and activation of complement cascade through the classical pathway

2)antibody May cause cell destruction through phagocytosis by macrophages

3)antibody and complement may attract neutrophils

4)antibody-dependent cell-mediated cytotoxicity

5)does not destroy target cell, but causes it to malfunction


Antibody-dependent cell-mediated cytotoxicity


antibodies attached to target cell cause destruction by macrophages, eosinophils, and NK cells


Type III immune complex mediated hypersensitivity


Caused by antigen-antibody (immune) complexes that are formed in the circulation and deposited later

in vessel walls or extravascular tissues


Hypocomplementemia

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