What neurochemical abnormality is most consistently described in Alzheimer disease of moderate severity. - ANS Decreased choline acetyltransferase activity
Which of the following sources of pain is thought to have a primarily central (non-nociceptive) mechanism?
a) cancer pain
b) fi...
What neurochemical abnormality is most consistently described in Alzheimer disease of
moderate severity. - ANS Decreased choline acetyltransferase activity
Which of the following sources of pain is thought to have a primarily central (non-nociceptive)
mechanism?
a) cancer pain
b) fibromyalgia
c) osteoarthritis
d) diabetic neuropathy
e) postherpetic neuralgia - ANS b) fibromyalgia
A patient presents with mild memory impairment, tearfulness, insomnia, and blurry vision. The
patient acts as if blind, cannot locate objects in the visual field, has left-right disorientation and
alexia, and misses objects when instructed to reach for them. The patient only identifies a single
object in a drawing of overlapping objects. Despite requiring prompts to visually follow objects,
cranial nerves, motor function, reflexes, and movement and color detection are otherwise intact.
What is the most likely cause of the visual disturbance? - ANS Cerebral infarct
Variable phenotypic expression of 15q13 deletion depends on whether the encoding gene is
derived from the father or the mother. This phenomenon is commonly referred to as - ANS
Genomic imprinting
A patient hospitalized for burns sustained in a house fire one week prior is experiencing
recurrent nightmares and frequent, intrusive memories about the fire accompanied by concern
that the patient seems depressed, is sleeping poorly and startles when someone enters the
room without knocking. On exam, the patient is distracted, sometimes irritable, and has labile
affect. What is the most likely diagnosis? - ANS Acute stress disorder
What is an example of epigenetic gene regulation? - ANS Addition of methyl group to a
histone around which DNA is coiled.
What sex hormone is most responsible for sexual differentiation in fetal brain development? -
ANS Testosterone (causes brain/body to be masculinized and defeminized)
,What psychiatric disorder occurs most frequently with secondary enuresis? - ANS ADHD
The psychiatrist is concerned about a colleague's behavior and notifies the State's physician
health program, which conducts an intervention. The physician should be referred for
professional evaluation/treatment in which scenario?
A) drinks wine with diner
B) has experienced depression and been hospitalized in past
C) has bipolar disorder and is euthymic/med compliant
D) uses cocaine occasionally but not habitually, on days off, negative utox
E) aggressive toward patients on 3 different occasions during ED shifts - ANS E
Abnormalities in which of the following components of the neurological examination would
indicate cerebellar dysfunction? - ANS Rapid alternating movements
Excessive activation of which of the following receptors is thought to contribute to cell death in
Alzheimer disease? - ANS NMDA
In behavior mastery training, which of the following techniques teaches individuals with sexual
addiction to identify factors that increase the likelihood of symptomatic sexual behavior? - ANS
Risk management
A patient has been prescribed a second-gen antipsychotic for just over a year. Since starting the
medication, her libido is markedly lower, and she has experienced irregular menstrual cycles.
Which lab test would have greatest diagnostic value at this point? - ANS Prolactin
A 58 year old patient develops progressive weakness and tingling two weeks after receiving a
vaccination. Examination reveals weakness and decreased sensation in the legs, as well as
absent DTRs in arms and legs. Imaging of the brain and spine is normal. Which test will confirm
the most likely diagnosis? - ANS Nerve conduction studies
Which of the following is among the first steps taken by a public school to address a student's
difficulty being successful academically? - ANS Initiate a response to intervention plan
Which of the following nuclei of the hypothalamus is the major site for Neuropeptide Y
synthesis? - ANS Arcuate nucleus
Which type of group therapy encourages high intragroup dependence and less group leader
dependence? - ANS Transactional
Which mechanism is the most likely cause of anosmia in patients infected with COVID19? -
ANS Direct viral involvement of the nasal epithelium
, An argumentative 10 year old who displays persistent anger outbursts, vindictiveness, and
deliberately annoys adults most likely has what disorder? - ANS Oppositional defiant
disorder
What outcome has been demonstrated to improve as a result of peer support services in the
treatment of people with mental illness? - ANS Social functioning
Electroconvulsive therapy is indicated for which of the following conditions?
A) Dissociative fugue
B) Serotonin syndrome
C) Intermittent explosive disorder
D) OCD
E) NMS - ANS E) NMS
Which white matter tracts connects the temporal and orbitofrontal cortices? - ANS Uncinate
fasiculus
Cingulum - ANS Connects frontal, temporal, and parietal lobes and also subcortical nuclei
to cingulate gyrus
Arcuate fasiculus - ANS Connects Wernicke's and Brocas
Inferior longitudinal fasciculus - ANS Connects occipital and temporal lobes
Superior longitudinal fasciculus - ANS Connects frontal lobe and ipsilateral hemisphere
The Clinical Pharmacogenetics Implementation Consortium dosing guidelines for
antidepressants are based on genetic variations in _______. - ANS CYP450 enzymes
Which molecular mechanism is best supported as a possible explanation for how early life
stress could lead to the development of psychiatric disorders in adulthood? - ANS DNA
methylation
Postpartum depression has been consistently associated with which outcome in children? -
ANS Infant growth impairment
A patient is convinced that their boss hates them, despite objective evidence to the contrary.
The patient's belief is best described by which defense mechanism? - ANS Projection
(attributing one's own unacceptable thoughts/feelings/motives onto another person)
Denial - ANS Blocking external events from awareness
Introjection - ANS Unconscious adoption of ideas/attitudes of others
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