Anti-Emetics MCQ UPDATED ACTUAL Exam Questions and CORRECT Answers
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Module
Anti-Emetics
Institution
Anti-Emetics
Anti-Emetics MCQ UPDATED ACTUAL
Exam Questions and CORRECT Answers
Name 2 phenothiazines. What receptors do they block? - CORRECT ANSWER-
Promethazine (Phenergan)-D2 blockade in CTZ + H1
Prochlorperazine (Compazine)-D2 blockade
Name an anti-cholinergic anti-emetic? What kind of nausea is it ...
Anti-Emetics MCQ UPDATED ACTUAL
Exam Questions and CORRECT Answers
Name 2 phenothiazines. What receptors do they block? - CORRECT ANSWER✔✔-
Promethazine (Phenergan)-D2 blockade in CTZ + H1
Prochlorperazine (Compazine)-D2 blockade
Name an anti-cholinergic anti-emetic? What kind of nausea is it good for? - CORRECT
ANSWER✔✔- Scopolamine (Transderm Scop)
Patch
Good for vertigo/motion sickness/vestibular surgery
Blocks M receptors in vestibular system
Apply patch evening before surgery or 4h before
Which phenothiazine has a black box warning? What is it for? - CORRECT ANSWER✔✔-
Promethazine (Phenergan) -Black box warning for tissue damage if IV admin
Major S/E of dopamine anatgonists (Phenothiazines)? - CORRECT ANSWER✔✔- EPS is
the most severe
Also have some anticholinergic activity
Compazine (Prochlorperazine) can cause hypotension
Phenergan (Promethazine) can cause sedation
Name two antihistamine anti-emetics and what kind of nausea/vomiting are they good for? -
CORRECT ANSWER✔✔- Hydroxyzine (Atarax)
Dimenhydrinate (Dramamine)
OTC
H1 blockade in the vestibular apparatus & vomiting center
Give after starting anesthesia
Good for vestibular type surgery, motion sickness, vertigo induced vomiting
Drowsiness, Anticholinergic S/E
, Don't give Atarax during pregnancy
Droperidol (Inapsine) is what class of anti-emetic? - CORRECT ANSWER✔✔-
Antidopaminergic
D2 blockade in the CTZ
Butyrophenone class
Give at end of surgery
Can cause drowsiness, hypotension, reflex tachycardia
What is the black box warning for Droperidol (Inapsine)? - CORRECT ANSWER✔✔- QT
interval prolongation
Torsades
What are the 3 classes of antidopaminergic anti-emetics? - CORRECT ANSWER✔✔-
Phenothiazines
Butyrophenone
Benzamide
Metoclopramide (Reglan) works on which receptors? - CORRECT ANSWER✔✔-
Benzamide Anti-dopaminergic
Central D2 antagonist in the CTZ
Works peripherally in the GI tract as well
So....good for visceral vagal induced vomiting (toxins, GI distention, infection, mucosal
irritation by targeting the D2 receptors in the GI as well, but serotonin receptors dominant
more than D2 receptors in GI so serotonin antagonists would work better for this kind of NV)
What is the black box warning for Metoclopramide (Reglan)? - CORRECT ANSWER✔✔-
Tardive Dyskinesia-involuntary movements of the perioral area (tongue, mouth, jaw, eyelids,
or face)
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