Advanced Pharmacology NUR6521 MidTerm Exam *Q&A* |Verified Study Set|
2025/2024
What is the primary therapeutic use of beta-blockers?
To reduce heart rate and blood pressure in cardiovascular conditions
What mechanism allows aspirin to provide anti-inflammatory effects?
Inhibition of cyc...
Advanced Pharmacology NUR6521 Mid-
Term Exam *Q&A* |Verified Study Set|
2025/2024
What is the primary therapeutic use of beta-blockers?
To reduce heart rate and blood pressure in cardiovascular conditions
What mechanism allows aspirin to provide anti-inflammatory effects?
Inhibition of cyclooxygenase (COX) enzymes, leading to reduced prostaglandin synthesis
How does the pharmacokinetics of a drug influence its therapeutic effect?
By determining the drug's absorption, distribution, metabolism, and excretion in the body
What is the role of anticoagulants in the management of thromboembolic disorders?
To prevent clot formation and reduce the risk of stroke or deep vein thrombosis
What is the primary action of angiotensin-converting enzyme (ACE) inhibitors?
To inhibit the conversion of angiotensin I to angiotensin II, leading to vasodilation and
decreased blood pressure
What is the therapeutic effect of corticosteroids in treating inflammatory diseases?
To suppress the immune response and decrease inflammation
1
,How does metformin lower blood glucose levels in patients with type 2 diabetes?
By decreasing hepatic glucose production and increasing insulin sensitivity
What adverse effect should be monitored in patients taking lithium for bipolar disorder?
Renal function and thyroid function due to potential nephrotoxicity and hypothyroidism
What is the primary mechanism of action of calcium channel blockers in the treatment of
hypertension?
By inhibiting calcium entry into vascular smooth muscle, resulting in vasodilation
What are the common side effects associated with opioid analgesics?
Respiratory depression, constipation, and sedation
How do selective serotonin reuptake inhibitors (SSRIs) treat depression?
By inhibiting the reuptake of serotonin in the brain, increasing its availability
What is the therapeutic use of nitroglycerin in patients with angina?
To dilate coronary arteries and improve blood flow to the heart muscle
How does warfarin exert its anticoagulant effect?
By inhibiting vitamin K-dependent clotting factors in the liver
2
, What are the primary adverse effects of long-term use of corticosteroids?
Osteoporosis, weight gain, and increased risk of infections
What is the mechanism of action of statins in lowering cholesterol levels?
Inhibition of HMG-CoA reductase, reducing cholesterol synthesis in the liver
What is the significance of the first-pass effect in drug metabolism?
It reduces the bioavailability of orally administered drugs as they are metabolized by the
liver before reaching systemic circulation
How do inhaled corticosteroids help in managing asthma?
By reducing inflammation and mucus production in the airways
What is the primary indication for using proton pump inhibitors (PPIs)?
To treat gastroesophageal reflux disease (GERD) by reducing gastric acid secretion
What is the action of albuterol in asthma management?
As a bronchodilator, it relaxes bronchial smooth muscle to relieve bronchospasm
What laboratory value should be monitored in patients taking digoxin?
Serum potassium levels to prevent toxicity
3
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