NUR6521 Advanced Pharmacology
Study Guide *Q&A* |Verified Study Set|
2025/2024
What is the primary mechanism of action of statins in cholesterol management?
They inhibit HMG-CoA reductase, which reduces cholesterol synthesis in the liver.
How do proton pump inhibitors (PPIs) alleviate symp...
NUR6521 Advanced Pharmacology
Study Guide *Q&A* |Verified Study Set|
2025/2024
What is the primary mechanism of action of statins in cholesterol management?
They inhibit HMG-CoA reductase, which reduces cholesterol synthesis in the liver.
How do proton pump inhibitors (PPIs) alleviate symptoms of gastroesophageal reflux disease
(GERD)?
By irreversibly blocking the hydrogen-potassium ATPase enzyme in the gastric parietal cells,
reducing gastric acid secretion.
What is the therapeutic purpose of using beta-adrenergic agonists in respiratory conditions?
To relax bronchial smooth muscles, providing bronchodilation for conditions like asthma and
COPD.
What are the potential side effects of long-term corticosteroid therapy?
Osteoporosis, hypertension, weight gain, and increased risk of infections.
How does the mechanism of action of ACE inhibitors benefit patients with heart failure?
By inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation and
decreased workload on the heart.
1
, What monitoring is essential for patients on lithium therapy?
Regular monitoring of serum lithium levels, kidney function, and thyroid function to avoid
toxicity.
How does metformin work to control blood sugar levels in type 2 diabetes?
By decreasing hepatic glucose production and improving insulin sensitivity in peripheral
tissues.
What are the primary indications for using anticoagulants like warfarin?
To prevent thromboembolic events such as stroke and deep vein thrombosis.
What is the significance of therapeutic drug monitoring in patients receiving aminoglycosides?
To avoid toxicity and ensure therapeutic effectiveness by measuring drug levels in the blood.
How do antiepileptic drugs stabilize neuronal membranes?
By modulating ion channels and neurotransmitter levels to prevent excessive neuronal
excitability.
What are the common adverse effects of thiazide diuretics?
Hypokalemia, hyponatremia, and increased uric acid levels leading to gout.
What is the mechanism of action of glucagon in hypoglycemic emergencies?
2
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