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BMS 602 Final Exam Latest Update
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BMS 602 Final Exam Latest UpdateHow can a B cell be distinguished from a T cell?
A. B cells have a large nucleus-to-cytoplasm ration
B. B cells have surface immunoglobulin
C. T cells mature in the bone marrow
D. B cells have a sheep red-blood cell receptor - Answer B. B cells have surface
immunoglobulin
A defect in the C1 component of complement would affect which of the pathways?
A. Alternate Complement Activation
B. Classical Complement Activation
C. Alternative and Classical Complement Activation
D. None of the above - Answer B. Classical Complement Activation
Which antibody class/ isotype is found on the surface of B cells?
A. IgG
B. IgM
C. IgD
D. IgE
E. IgG and IgD
F. IgM and IgD - Answer F. IgM and IgD
What distinguishes MHC I from MHC II?
A. MHC I acquires antigenic peptides from the inside of the cell
B. MHC I binds an 8-amino-acid peptide
C. MHC I presents peptides the the T cell receptor
D. MHC II presents antigenic peptides to CD8 T cells - Answer A. MHC I acquires
antigenic peptides from the inside of the cell
During antibody production, VDJ recombination joins V, D, and J sequences by:
,A. Splicing exons of RNA
B. Recombining DNA at recombination signal sequences (RSS)
C. Enzymatically linking V, D, and J peptides
D. None of the above - Answer B. Recombining DNA at recombination signal sequences
(RSS)
Which of the following is NOT true about T independent antigens:
A. The antigen is a large repetitive structure
B. The antigen can activate B cells directly
C. The antigen produces the 5 different classes of antibody independent of T cell
interaction
D. The antigen stimulates B cells to produce IgM antibody - Answer C. The antigen
produces the 5 different classes of antibody independent of T cell interaction
The cell wall of bacteria is made up of:
A. Chains of N-Acetylglucosamine and N-Acetylmuramic acid
B. Chains of N-Acetylglucosamine and N-Acetylmuramic acid linked by peptide
crosslinks
C. Chains of N-Acetylglucosamine and N-Acetylmuramic acid linked by lipid crosslinks
D. Chains of N-Acetylclucosamine and N-Acetylmuramic acid linked by carbohydrate
crosslinks - Answer B. Chains of N-Acetylglucosamine and N-Acetylmuramic acid linked
by peptide crosslinks
In response to an external signal the sensor kinase of a two-component signal
transduction system:
A. Phosphorylates (adds a phosphate to) itself and then phosphorylates a response
regulator
B. Phosphorylates itself and then interacts with the promoter of an operon
C. Phosphorylates a response regulator
D. Phosphorylates the promoter of an operon - Answer A. Phosphorylates (adds a
phosphate to) itself and then phosphorylates a response regulator
Which of the following is true about sterilization:
A. Sterilization destroys all living microbes, spores, and viruses
B. Sterilization reduces the number of pathogenic microbes or discourages their growth
,C. Sterilization requires the application of heat to a contaminated object
D. Sterilization requires the application of a chemical agent to a contaminated object -
Answer A. Sterilization destroys all living microbes, spores, and viruses
Malaria is a disease caused by the protozoan Plasmodium falciparum. Humans contract
the disease through the bite of an Anopheles mosquito. This is an example of what kind
of disease transmission:
A. Direct Transmission
B. Indirect Transmission
C. Opportunistic Infection
D. Parasitism - Answer B. Indirect Transmission
Does the production of IgA antibody require interaction of B cells with T cells? - Answer
Yes, T cell- B cell interaction causes cytokine release that allows class switch reaction
A defective C2 complement protein would affect which of the following activation
pathways?
A. Alternate Complement Activation
B. Classical Complement Activation
C. Alternative and Classical Complement Activation
D. None of the above - Answer B. Classical Complement Activation
Which of the following antibodies is the MOST abundant in the mucous that lines mucous
membranes?
A. IgG
B. IgM
C. IgE
D. IgA
E. IgD - Answer D. IgA
While working out at Hamel Recreation Center, Charlie the Freshman suffers a mild
abrasion to his hand while putting away a kettle drum. The injury introduces
Streptococcus pyogenes into the epidermal skin layer. Which of the following is a
possible outcome for Charlie's encounter with Streptococcus pyogenes.
A. S. pyogenes transiently colonizes Charlie's skin
B. S. pyogenes permanently colonizes Charlie's skin
, C. S. pyogenes causes disease
D. All of the above - Answer D. All of the above
Which of the following is an example of mutualism?
A. Micrococcus luteus living on human skin doing no harm nor providing no benefit to
the human host
B. Escherichia coli living int he human intestinal tract providing the human host vitamins
B and K
C. Streptococcus pyogenes living int he oropharynx of the human host and causing
pharyngitis
D. Corynebacterium diphtheria living in the human nasal passages moving to the
nasopharynx causing harm to the human host - Answer B. Escherichia coli living in the
human intestinal tract providing the human host vitamins B and K
Exotoxins are:
A. Proteins actively secreted by bacteria that damage the host
B. Bacterial products or components that are released by bacteria as part of normal
growth and cause an immune response
C. Virulence genes transferred from the bacteria to the host
D. Bacterial proteins that allow adherence to the bacteria to host tissues - Answer A.
Proteins actively secreted by bacteria that damage the host
Which of the following complement proteins promote phagocytosis of microbial
pathogens by acting as opsonins?
A. C1, C2, Factor B
B. C2a, C2b, C3b
C. C3a, C5a
D. C3b - Answer D. C3b
Virulence is:
A. The measure of the ability of an organism to cause disease
B. The measure of the ability of an organism to infect a host
C. The measure of the severity of a disease caused by an organism
D. All of the above - Answer C. The measure of the severity of a disease caused by an
organism
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