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UC 8024 Pharm Exam 4 Question and answers correctly solved 2024/2025 £15.15   Add to cart

Exam (elaborations)

UC 8024 Pharm Exam 4 Question and answers correctly solved 2024/2025

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  • NURS 8024
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  • NURS 8024

UC 8024 Pharm Exam 4 Question and answers correctly solved 2024/2025 UC 8024 Pharm Exam 4 Biguanides (Metformin) - correct answer First line agent for DMII MOA: Decreases liver glucose production ADE: diarrhea and abdominal pain BBW: Lactic Acidosis - rare Contra: Pts with rena...

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  • October 17, 2024
  • 22
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NURS 8024
  • NURS 8024
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UC 8024 Pharm Exam 4
Biguanides (Metformin) - correct answer ✔First line agent for DMII


MOA: Decreases liver glucose production


ADE: diarrhea and abdominal pain


BBW: Lactic Acidosis - rare


Contra: Pts with renal impairment


Sulfonylureas - correct answer ✔MOA: Increased endogenous insulin
secretion (binding to pancreatic beta receptors to trigger insulin release)


ADE: Hypoglycemia (combined w/ other agents), wt gain, rash (sulfa), HA,
N/V, photosensitivity


Caution: Renal/hepatic impairment


Thiazolidinediones (TZDs) - correct answer ✔MOA: Increases muscle and
adipose cell sensitivity to insulin & suppresses liver glucose production


ADE: Wt gain, edema, hypoglycemia (if taken w/ insulin), possible increased
fracture risk (women),


BBW: CHF

,Caution: hepatic impairment


Meglitinides - correct answer ✔MOA: stimulate insulin secretion in presence
of glucose


ADE: Hypoglycemia (if patient has abnormal eating schedule), wt gain, SJS,


Contra: with use of gemfibrozil


Caution: hepatic dysfunction


Medications in class: Repaglinide (Prandin), Nateglinide (Starlix)


GLP-1 Agonists - correct answer ✔MOA: increases glucose-mediated insulin
release. suppresses glucagon secretion, delays gastric emptying


ADE: wt. loss, GI symptoms, pancreatitis


Caution: renal dysfunction, severe gastroparesis


Medications in class: exenatide (Byetta), liraglutide (Victoza, Dulaglutide
(Trulicity)


SGLT2 Inhibitors - correct answer ✔MOA: Block renal glucose resorption -
causes glucosuria

, ADE: GU infections, Wt loss, polyuria, dehydration


Contra: severe renal impairment


**Fracture risk
***Dose-related increase in LDL


Alpha-glucosidase Inhibitors - correct answer ✔MOA: blocks enzymes that
digest starch in small bowel; causing decreased glucose absorption


ADE: flatulence, abdominal discomfort


Hypoglycemia risk with secretagogue


Contra: pts with IBS or cirrhosis


Medications in this class: acarbose (Precose) and miglitol (Glyset)


DPP-4 Inhibitor - correct answer ✔MOA: inhibits breakdown of glucagon-like
peptide-1 secreted during meals


Oral medication: Increased glucose-mediated insulin release, delays gastric
emptying (promotes satiety)


ADE: Pancreatitis, NV, hypersensitivity (angioedema, anaphylaxis)


Caution: renal insufficiency

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