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Exam (elaborations)

PACOP PCOL Exam Questions With Correct Answers

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©SIRJOEL EXAM SOLUTIONS 12/3/2024 11:27AM PACOP PCOL Exam Questions With Correct Answers Mechanism of action of local anesthetics - answerBlock sodium channels thereby stopping axonal conduction The ff are factors that affect the absorption of the drug from the GI tract EXCEPT: a. SA of sit...

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  • October 20, 2024
  • 13
  • 2024/2025
  • Exam (elaborations)
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  • PCOL
  • PCOL
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©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM



PACOP PCOL Exam Questions With
Correct Answers


Mechanism of action of local anesthetics - answer✔Block sodium channels thereby stopping

axonal conduction

The ff are factors that affect the absorption of the drug from the GI tract EXCEPT:

a. SA of site of absorption

b. blood flow

c. physical state of drug

d. conc of drug at absorption site


e. protein binding - answer✔E. protein binding


Continued stimulation of cells with agonists results to which of the ff:

a. desensitization

b. up-regulation

c. down-regulation

d. A and B

, ©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM


e. A and C - answer✔E. A and C (desensitization and down-regulation)


Drug that lacks intrinsic efficacy but retains affinity and competes with the agonist for the

binding site on the receptor - answer✔competitive antagonist


this type of drug produces its effect by binding a site on the receptor distinct from that of the

primary agonist and thereby changing the affinity of the receptor for the agonist - answer✔non-

competitive antagonist

In this type of study, participants are blinded to treatment assignment, but investigators are not. -

answer✔single blinded study


The neurotransmitter of all preganglionic autonomic fibers and all postganglionic

parasympathetic fibers - answer✔Acetylcholine


the release of acetylcholine and other neurotransmitters by exocytosis is inhibited by -

answer✔botulinum toxin


all of the ff enzymes are involved in the biosynthesis of epinephrine from tyrosine EXCEPT:

a. tyrosine hydroxylase

b. aromatic L-amino acid decarboxylase

c. dopamine Beta-hydroxylase

d. phenylethanolamine-N-methyl transferase

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