Exam (elaborations)
USMLE STEP 2 CK QUESTIONS AND ANSWERS
- Module
- Institution
USMLE STEP 2 CK QUESTIONS AND ANSWERS
[Show more]
Seller
Follow
GEEKA
Reviews received
Content preview
USMLE STEP 2 CK QUESTIONS AND ANSWERSpregnant with active HBV - Answers-tx newborn with HBIG and HBV vaccine
Beck's triad for tamponade - Answers-hypotension, JVD, muffled heart sounds (also
pulsus paradoxus). Electrical alternans
subarachnoid hemorrhage - Answers-increased ADH and BNP --> hyponatremia. Tx -
water restriction
coccidioidomycosis - Answers-SW US, central/south America. Pulm infection - dry
cough, weight loss, pleuritic chest pain, erythema multiforme/nodosum, arthralgias
histoplasmosis - Answers-SE US, mid Atlantic, central US, caves. Acute PNA, but
usually asymptomatic. HIV disseminated infection- hilar LAD, pneumonitis,
pancytopenia, hepatosplenomegaly, palatal ulcers. tx- IV amphotericin B followed by
lifelong itraconazole.
Blastomycosis - Answers-central US (most in Wisconsin). Often asymptomatic or flu-like
Sx. Systemic disease- lytic bone lesions, pulmonary infection, skin lesions. Dx- broad-
based budding yeast. Tx- itraconazole, amphotericin B
aspergillosis - Answers-invasive in IMCD. CXR - cavitary lesions. CT - pulm nodules,
halo sign, air crescent
sporotrichosis - Answers-subcutaneous infection. Gardeners. Travel up lymphatics for
nodules on forearms
cryptococcus - Answers-pulm infection often asymptomatic. Usually
meningoencephalitis in HIV with CD4<200
hemochromatosis infections - Answers-Listeria monocytogenes, Yersinia enterocolitica,
septicemia - Vibrio vulnificus
Narcolepsy treatment - Answers-methyldphenidate, modafinil, antidepressants (for
cataplexy)
galactorrhea - Answers-test B-HCG, prolactin, TSH
septic abortion - Answers-cervical/blood cultures, antibiotics, gentle suction currettage
Lesch-Nyhan - Answers-x-linked recessive, HPRT deficiency, increased uric acid. Sx -
self mutilation, dystonia, spacticity, gout. Presents at 6 months.
minimal change disease - Answers-tx - prednisone, cyclophosphamide for resistant
cases/frequent relapse
,Sturge-Weber - Answers-seizures, retardation, trigeminal port-wine stain, hemi neuro
findings, tramline intracranial calcifications
tuberous sclerosis - Answers-seizures, retardation, intracranial calcifications (tubers),
ashleaf spots, adenoma sebaceum (red papules on face)
osteogenesis imperfecta - Answers-autosomal dominant. Type 1 collagen problem. Type
2 most severe with perinatal fractures and often intrauterine death. Blue sclera,
fractures, hypotonia, hearing loss, joint hypermobility, dentinogenesis imperfecta
polymyalgia rheumatica - Answers-neck/shoulder/hip pain/stiffness. >50 years old, high
ESR. Tx- low dose prednisone, high dose for temporal arteritis
massive blood transfusion - Answers-citrate anticoagulant --> chelates Ca and Mg -->
low Ca --> paresthesias, hyperactive reflexes
nephrotic syndrome - Answers-dyslipidemia, accelerated atherosclerosis,
hypercoagulable, risk for MI/stroke, higher infxn susceptibility. Can have renal vein
thrombosis, usually with membranous GN
aortic regurgitation - Answers-early diastolic (mild) to holodiastolic (severe) murmur.
Bounding pulses. Tx- decrease afterload with DHP Ca-channel blockers, ACEi, NOT
beta blockers.
mycoplasma PNA - Answers-erythema multiforme. No cell wall so not on gram stain
candidal vulvovaginitis - Answers-pseudohyphae. In IMCD and Abx treated people. Tx-
oral fluconazole, topical nystatin
nonseminomatous germ cell tumor - Answers-large anterior mediastinal mass, young
males. High HCG and AFP.
seminoma - Answers-high HCG but normal AFP
thymoma - Answers-associated with myasthenia gravis, pemphigus
hepatocellular carcinoma - Answers-high AFP but normal HCG
choriocarcinoma - Answers-gestational trophoblastic disease usually in molar
pregnancy. Very high HCG
C. dif diagnosis - Answers-cytotoxin assay of stool
Erb-Duchenne palsy - Answers-C5, C6. waiter's tip, absent Moro but intact grasp
,Klumpke's paralysis - Answers-C7, C8, T1. hand paralysis, Horner's (ptosis, miosis)
dermatitis herpetiformis - Answers-papulovesicular, pruritic. Associated with Celiac. Dx -
IgA anti-endomysial Ab, anti-gliadin
phenelzine - Answers-MAOi antidepressant. Avoid tyramine (aged meat/cheese) -->
HTN crisis
CMV esophagitis - Answers-in HIV. Dysphagia, odynophagia, shallow ulcers,
intranuclear/cytoplasmic inclusions. Tx- ganciclovir IV
HSV esophagitis - Answers-in HIV. Small ulcers with volcano-like appearnace.
Eosinophilic intranuclear inclusions. Tx- acyclovir
candidal esophagitis - Answers-most common HIV esophagitis. Tx - oral fluconazole
splenic rupture - Answers-ex-lap if unstable. CT if stable
pseudocyesis - Answers-pregnancy conversion disorder
prolactin - Answers-stimulated by serotonin and TRH, inhibited by dopamine.
Hypothyroid --> amenorrhea/galactorrhea
adenomyosis - Answers-endometrial glands in myometrium. Usually > 40yo,
dysmenorrhea, menorrhagia, enlarged symmetric uterus. Must curettage to r/o
endometrial carcinoma
leiomyoma/fibroids - Answers-irregular shaped uterus
endometriosis - Answers-uterus not enlarged. Dysmenorrhea, dyspareunia, dyschezia.
Dx- laparoscopy. Tx- OCPs
aminoglycosides - Answers-amikacin, gentamicin, tobramicin. ototoxic, nephrotoxic.
Gentamicin very ototoxic
hydroxychloroquine - Answers-DMARD. Treats SLE. SE - retinopathy/corneal damage
(need q6month eye exams), GI, hemolysis in G6PD
methotrexate SE - Answers-DMARD. Inhibits folate metabolism. Macrocytic anemia, GI,
hepatotoxic, ILD, alopecia, pancytopenia
premature ovarian failure - Answers-low estrogen, high FSH > LH, <40yo
hyperparathyroidism - Answers-hypercalcemia - stones, bones, groans, psyciatric
overtones, polydipsia, polyuria. pseudogout. Also sometimes HTN
, low-grade (without mets) gastric MALT lymphoma - Answers-H pylori association. Tx-
PPI, clarithromycin, amoxicillin
Jarisch-Herxheimer rxn - Answers-primary/secondary syphilis treated with penicillin -->
spirochetes die --> immune complexes --> looks like syphilis flare-up
INH SE - Answers-hepatitis, peripheral neuropathy/ataxia (give pyridoxine)
fanconi anemia - Answers-pancytopenia, congenital anomalies, presents 4-12yo.
Autosomal recessive. Skin changes
diamond-blackfan - Answers-pure red cell aplasia, congenital anomalies. Presents 3
months old. Tx - steroids, possibly transfusion
transient erythroblastopenia of childhood - Answers-RBC aplasia. Presents 6mo - 5yo
psoriatic arthritis - Answers-DIP, dactylitis. Tx- NSAID, anti-TNF, methotrexate, NOT
steroids
RA - Answers-MCP, PIP, not DIP. Tx- methotrexate, hydroxychloroquine, TNF inhibitors
(infliximab, etanercept)
OA - Answers-DIP
adjustment disorder - Answers-within 3 months of event, lasts < 6 months post-event.
Tx- cognitive/psychodynamic psychotherapy
cushing's - Answers-high corticosteroids, central obesity, DM, proximal muscle
weakness, psychosis, thin skin, purple striae, osteoporosis, hypokalemic alkalosis,
secondary HTN
APML - Answers-Tx- ATRA
CML - Answers-leukocytosis, anemia, increased granulocytic forms (PMNs, bands), leuk
alk phosh low (high in leukemoid reaction). Philadelphia chromosome, t(9:22), BCR-ABL
gene. Tx- tyrosine kinase inhibitors (imatinib). Usually > 50yo
McCune-Albright - Answers-3 P's - precocious puberty, pigmentation (café-au-lait),
polyostotic fibrous dysplasia. Associated with other endocrine d/o's - hyperthyroid,
prolactinoma, growth hormone, cushing's
von Recklinghausen/NF1 - Answers-autosomal dominant. café-au-lait, axillary/genital
freckling, Lisch nodules, neurofibromas, bony lesions, tumors.
NF2 - Answers-autosomal dominant. brain tumors, bilateral acoustic neuromas, other
tumors.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller GEEKA. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £10.12. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
56326 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now