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MICN201 Infection and Immunity (Antibiotics) Exam
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MICN201 Infection and Immunity (Antibiotics) ExamWhat is bacteriostatic? - Answer Something that inhibits bacterial multiplication without
killing them
What is bactericidal? - Answer Something that kills bacteria
What is MIC? - Answer The minimum concentration for a substance to be bacteriostatic
What is MBC? - Answer The minimum concentration for a substance to be bactericidal
What is the site of action for beta lactams? - Answer Cell wall peptidoglycans
What is the site of action for glycopeptides? - Answer Cell wall peptidoglycans
What is the site of action for aminoglycosides? - Answer Ribosomes (Protein Synthesis)
What is the site of action for macrolides? - Answer Ribosomes (Protein Synthesis)
What is the site of action for quinolones? - Answer Nucleus (DNA replication)
What antibiotic classes work on the cell wall peptidoglycan? - Answer Beta lactams and
glycopeptides
What antibiotic classes work on protein synthesis? - Answer Aminoglycosides and
macrolides
, What antibiotic classes work on DNA replication? - Answer Quinolones
What are the main mechanisms of antibiotic resistance? - Answer An enzyme degrades
antibiotics or the antibiotic target is altered
What are the main resistances present in Staph Aureus? - Answer Penicillin and
methicillin
What are the criteria for a good antibiotic? - Answer It must reach the site of the
infection, penetrate host cells if the bacteria is intracellular, must be the appropriate
dose, frequency and duration.
What are examples of beta lactams? - Answer Penicllin, cephalosporins, carbapenems.
How are beta lactams administered? - Answer Orally mostly. Some injected.
What is an example of an aminoglycoside? - Answer Gentamicin.
How is gentamicin administered? - Answer IV or IM
When is gentamicin used? - Answer Gram negative infections and staph aureus
infections
What is an example of a fluoroquinolone? - Answer Ciprofloxacin
What are fluoroquinolones used for? - Answer Gram negative bacteria and respiratory
tract infections
What is an example of a macrolide? - Answer Erythromycin
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