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Urinalysis and Body Fluids: Chapter 7 Renal Disease Exam Questions With Solutions £11.98   Add to cart

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Urinalysis and Body Fluids: Chapter 7 Renal Disease Exam Questions With Solutions

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Urinalysis and Body Fluids: Chapter 7 Renal Disease Exam Questions With Solutions How immunologic disorders damage the glomerulus - Increased serum immunoglobulins are deposited on the glomerular membranes - Immune system mediators: complement proteins migrate & produce change & damage to m...

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  • October 26, 2024
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Urinalysis and Body Fluids: Chapter 7 Renal
Disease Exam Questions With Solutions

How immunologic disorders damage the glomerulus - Increased serum immunoglobulins

are deposited on the glomerular membranes

- Immune system mediators: complement proteins migrate & produce change & damage to

membranes




Glomerulonephritis (definition) General term for sterile, inflammatory process affecting

the glomerulus




Urinalysis for Glomerulonephritis Hematuria


Proteinuria

RBC casts




Glomerulonephritis progression Acute > Chronic > Nephrotic Syndrome > Renal Failure




Types of Glomerular Disorders (11 Total: 9 Glomerulonephritis & 2 Nephrotic Syndrome)

Glomerulonephritis


1. Acute Poststreptococcal Glomerulonephritis

,Urinalysis and Body Fluids: Chapter 7 Renal
Disease Exam Questions With Solutions
2. Rapidly Progressive (Crescentic) Glomerulonephritis

3. Goodpasture Syndrome

4. Wegener Granulomatosis

5. Henoch-Schönlein Purpura

6. Membranous Glomerulonephritis

7. Membranoproliferative Glomerulonephritis (MPGN)

8. Chronic Glomerulonephritis

9. Immunoglobulin A Nephropathy (Berger Disease)




Nephrotic Syndrome

1. Minimal Change Disease (Lipid Nephrosis)

2. Focal Segmental Glomerulosclerosis (FSGS)




Etiology/Clinical Course: Acute Poststreptococcal Glomerulonephritis (AGN) - Fever,

edema around the eyes, oliguria, proteinuria, & hematuria

- Immune complexes deposit on glomerular membranes

- Group A streptococcal infections from strains with M protein in the cell wall

, Urinalysis and Body Fluids: Chapter 7 Renal
Disease Exam Questions With Solutions
Significant Test: Acute Streptococcal Glomerulonephritis (AGN) - Rapid anti-group A

streptococcal enzyme tests

---> Easier to diagnosis quickly

---> Decline in incidence with use of antibiotics




Etiology/Clinical Course: Rapidly Progressive (Crescentic) Glomerulonephritis - More

serious acute form -> renal failure

- Systemic immune disorder

---> Macrophages damage capillary walls

---> Fibrin: permanent damage to capillary tufts

- Some may have increased fibrin degradation products (FDP), cryoglobulins & IgA immune

complex depositions




UA (similar to AGN):

Progression (more abnormal):

- Elevated Protein

- Low GFR

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