The NoGrow1 gene will first be transcribed to make mRNA. Which of the
following polymerases transcribes mRNAs in eukaryotes? Right Ans - RNA
polymerase II
When transcription is completed, which of the following will terminate
transcription in eukaryotes? Right Ans - A nuclease will recognize
sequences in the RNA and cleave the RNA from the elongating strand
The mRNA transcript will also need to be processed. When does mRNA
processing begin? Right Ans - While transcription elongation is occurring
When the gene is transcribed, the resulting RNA must be protected from
nucleases. Which of the following protects the 5' end of an mRNA in
eukaryotes? Right Ans - A 7m-guanosine cap, in an atypical 5' to 5' linkage
between the two phosphate groups of neighboring nucleotides
The mRNA will be exported from the nucleus using exportin. Which of the
following will be bound to the exportin as it moves from the nucleus to the
cytoplasm? Right Ans - Both Ran-GTP and cargo
During nuclear import/export, which of the following is TRUE? Right Ans -
The GAP is in the cytoplasm
The transcript will be translated in the cytoplasm. Which of the following
statements is TRUE of translation initiation? Right Ans - The first amino
acid has a chemical block on the C-terminus, so the N-terminus is free for the
next amino acid to be added
In hotter oceans, a number of small RNAs also increase in expression. What is
the consequence of increasing the amount of small RNAs that perfectly
complement their target? Right Ans - The complementary mRNAs will be
degraded
Which of the following is true of splicing? Right Ans - Splicing begins when
the 2'OH of the branchpoint attacks the 5' end of the intron
, If the mRNA is transcribed and prepared for translation, which of the
following is TRUE of translation? Right Ans - ATP is required to bind the
amino acid to its tRNA
Which of the following is TRUE about the interaction between ligand and
receptor? Right Ans - Ligands and receptors can be modelled by induced fit
Which of the following is TRUE about G-protein coupled receptors in the
target cell? Choose all correct statements. Right Ans - They are inactivated
when GTP is hydrolyzed to GDP and phosphate
Which of the following best describes the relationship between the receptor
and the G-protein? Right Ans - A quaternary structure using non-covalent
bonds between sidechain atoms
Which of the following statements is TRUE about the cytoskeleton in general?
Right Ans - The cytoskeleton is strong and dynamic
The receptors are trans-membrane proteins. During the production of this
membrane protein, where did translation of this membrane protein begin?
Right Ans - A free ribosome in the cytoplasm
The receptors are trans-membrane proteins. During the production of this
membrane protein, where did translation of this membrane protein begin?
Right Ans - A free ribosome in the cytoplasm
During the production of this membrane protein, which of these is true of the
sugars added in the ER? Right Ans - They are N-linked and added to the
protein all at one time
During the process of protein production and localization, which of these is a
vesicle protein that will interact with proteins in the membrane to induce
membrane fusion? Right Ans - V-SNARE
The genes that code for these proteins are only accessible in some cell types.
Which of these terms describes DNA that is NOT accessible and where you
find these genes in other cell types. Right Ans - Heterochromatin
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