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Exam (elaborations)

NR 566 week 1 with 130 complete Solutions A+ GRADED

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  • NR 566

NR 566 week 1 with 130 complete Solutions A+ GRADED NR 566 week 1 with 130 complete Solutions A+ GRADED NR 566 week 1 with 130 complete Solutions A+ GRADED NR 566 week 1 with 130 complete Solutions A+ GRADED NR 566 week 1 with 130 complete Solutions A+ GRADED NR 566 week 1 with 130 complete So...

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  • November 13, 2024
  • 13
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR 566
  • NR 566
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NR 566 week 1 with 130 complete
Solutions A+ GRADED
NR 566 week 1 with 130 complete
Solutions A+ GRADED
CYP450 Inhibitors - ANSWER-Decrease Med Metabolism:
Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Kebonazole
Grapefruit juice
Quinidine

CYP450 Inducers - ANSWER-Accelerate Med Metabolism:
Carbamazepine
Rifampin
Alcohol
Phyenytoin
Griseofulvin
Phenobarbital
Sulfonylureas

Which antimicrobial is more likely to facilitate emergence of drug-resistant organisms
and superinfections? - ANSWER-Broad-spectrum antibiotics

Which antibiotic drug CLASSES are contraindicated in pregnancy? - ANSWER-
FLUOROQUINOLONES- potential cartilage damage risk
TETRACYCLINES-potential tooth damage and staining

Microbes four basic mechanisms for resisting drug? - ANSWER-1. Decrease the
concentration of a drug at its site of action.
2. Alter the structure of drug target molecules
3. Produce a drug antagonist
4. Cause drug inactivation.

Bactericicidal - ANSWER-Drugs that are directly lethal to bacteria.

Bacteriostatic - ANSWER-Drugs that can slow bacterial growth but do not cause cell
death.

What classes of antibiotics are resistant to C-Diff? - ANSWER-Aminoglycosides or
Cephalosporins

, NR 566 week 1 with 130 complete
Solutions A+ GRADED
What are generally the best antibiotics to treat C-Diff? - ANSWER-Flagyl or Vancomycin

Antibiotic Stewardship - ANSWER-Plan to Combat Antimicrobial Resistance

When is empiric therapy appropriate? - ANSWER-Patients with severe infections,
treatment can be initiated prior to test results (C&S).

What is the most common bacteria in CAP? - ANSWER-S.pneumoniae

Drug TX for S.pneumonia - ANSWER-Susceptible strains:
Penicillin G
Penicillin V
Amoxicillin
Resistant strains:
Cephalosporin
Ampicillin

Most common bacteria in UTI? - ANSWER-E.coli

1st line of TX for H.pylori - ANSWER-Clarithromcin+Amoxicillin+Esomeprazeole

2nd line:
Tetracyline+metronidazole+Bismuth subsalicylate + Esomeprazole

Sulfonamides can cause what in infants? - ANSWER-Kernicterus - a severe neurologic
disorder caused by displacement of bilirubin from plasma proteins.

Gentamicin can cause what to an infant if used during pregnancy? - ANSWER-
Irreversible hearing loss

Use of Tetracyclines in infants and children can cause what? - ANSWER-Staining of
teeth

Antibiotic that is safe during breatfeeding - ANSWER-Amoxicillin

MOA of beta-lactam antibiotics? - ANSWER-Disruption of bacterial cell wall

B-Lactam Drugs - ANSWER-Penicillin
Cephalosporins
Carbapenems
Monobactems (aztreonam)

Bactericidal Drugs - ANSWER-B-Lactam:

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