gms 6530 hyperlipidemia exam questions and answers
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GMS 6530 HYPERLIPIDEMIA EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS VERIFIED
Chylomicrons
- largest
- mostly triglycerides
- short life span
- broke down by LPL
VLDL
- mostly triglycerides
IDL
- cholesterol
- triglycerides
LDL
- cholesterol
- bad
HDL
- apolipoproteins
- little cholesterol
- good
LPL
, - lipoprotein lipase
- breaks down lipoproteins into free fatty acids
- lowers triglyceride levels
LDL receptors
- decrease with age
- located in liver
- control plasma cholesterol levels
Statins
- HMG-coA reductase inhibitors
- or's & ol's
- reduce cholesterol synthesis
- most effective in reducing LDL
- work in hepatocytes
Statins indirect action
- increase LDL receptors > increasing extraction of LDL by liver, decreasing plasma
concentration
- small decrease in VLDL (triglycerides) & HDL
-
Statin use
- hypercholesterolemia (increased LDL)
- mixed hyperlipidemia (increased LDL & VLDL)
- first line after MI
Statin side effects
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