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PHRM 4200: Biopharmaceutics Exam Questions With Correct Answers.

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©BRAINBARTER EXAM SOLUTIONS 2024/2025 ALL RIGHTS RESERVED. 1 | P a g e PHRM 4200: Biopharmaceutics Exam Questions With Correct Answers. Define biopharmaceutics. - answerthe study of how the physicochemical properties of drugs, dosage forms, and route of administration affect the rate and ext...

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  • December 3, 2024
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©BRAINBARTER EXAM SOLUTIONS 2024/2025

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PHRM 4200: Biopharmaceutics Exam
Questions With Correct Answers.


Define biopharmaceutics. - answer✔the study of how the physicochemical properties of drugs,

dosage forms, and route of administration affect the rate and extent of drug absorption


liberation and dissolution - answer✔solid state -> solution


The drug must be ___ to be absorbed. - answer✔in solution


Define bioavailability. - answer✔the rate and extent of therapeutically active drug reaching the

systemic circulation


F - answer✔bioavailability


absolute F - answer✔IV reference


relative F - answer✔compare formulation to a recognized standard (ex. market product or

topical vs oral)


Cmax - answer✔peak plasma concentration of drug


Tmax - answer✔time at the Cmax



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, ©BRAINBARTER EXAM SOLUTIONS 2024/2025

ALL RIGHTS RESERVED.
Where can the rate of absorption be found? - answer✔before the Cmax/Tmax


Where can the rate of elimination be found? - answer✔after the Cmax/Tmax


AUC - answer✔area under the curve; extent of absorption


Where can the extent of absorption be found? - answer✔area under the curve


ka - answer✔absorption rate


K - answer✔elimination rate; partition


What is the equation for the plasma vs time curve? - answer✔dX/dt = kaXa - KX


What happens when ka is increased? - answer✔elimination: same rate


Tmax: decreases


Cmax: increases


AUC: same


What happens to K when ka is increased? - answer✔stays the same (same elimination rate)


What happens to Tmax when ka is increased? - answer✔decreases (reaches Cmax faster)


What happens to Cmax when ka is increased? - answer✔increases


What happens to the extent of absorption when ka is increased? - answer✔stays the same

(AUC is equal)



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