Principle of Complementarity - Answers✔form determines function
anatomy determines the physiology that can take place
Physiology uses Gradients - Answers✔body takes advantage of gradients
can be natural or at expenditure of energy
Regulate protein functions by regulating its shape - Answers✔tagging (phosphorylation) changes
shape -> function
can be subtle or drastic
Negative feedback regulation is essential to homeostasis - Answers✔homeostasis
:normal/baseline/reference point
negative feedback loops allow us to restore homeostasis
What are the three principles of the cell theory? - Answers✔1) Cell is the basic structure &
functional unit of living organisms
2) Principal of complementary -> specific suocelular structures dictate biochemical activities ->
organelles in cells show functions of cells
3) continuity of life has similar basis -> meiosis & mitosis
Three structural/functional relationships of eukaryotic cells - Answers✔nucleus (except red
blood cells)
cytoplasm
plasma membrane
What do cells do all day while you're working? - Answers✔segregate (separate internal from
external)
transport & digest ( membrane trafficking)
identify alien invaders ( distinguish self from non self)
internal support
hold hands (cell to cell adhesion)
communicate (between cells)
build/remodel/demolish
clone
Plasma Membrane - Answers✔fluid mosaic model ( flexible like vegetable oil)
phospholipid bilayer ( fat molecule w/ head and tail)
- polar head -> hydrophilic -> containes phosphate
- nonpolar tail -> hydrophobic - > containes fatty acids
SELF ASSEMBLING
cholestoral -> mixed between nonpolar tails - > stiffens membrane -> decreases water solubility
of membrane
made up of CH groups
ampipathic molecule
no charge
ALL RIGHTS RESERVED.
glycolipids -> exposed on extracellular side
selectively permiable
Plasma Membrane structure - Answers✔2 fatty acid chains with a phosphate group and glycerol
backbone
What is an amphipathic molecule? - Answers✔a molecule that can interface between water and
lipid
ex. milk and eggs while baking help to combine water and oil
Give an example of how the plasma membrane is self-assembling. - Answers✔cloning
-> if you poke a hole in the membrane to extract DNA, the cell survives because the membrane
closes after the glass rod is extracted
What stabilizes the plasma membrane? - Answers✔cholesterol
what does cholesterol do to the membrane at different temps? - Answers✔High temps -> tiffins
cold temps -> more fluid
What is on the plasma membranes extracellular side? - Answers✔glycolipids and glycoproteins
(lipids/proteins w sugar attached)
What is the glycocalyx? - Answers✔Sugar group attached to the branching glycolipids and
glycoproteins
DETERMINES SELF FROM NONSELF
- each cell's is different and unique
What is an integral membrane protein? - Answers✔most are transmembrane -> extend through
hydrophobic & hydrophilic region (but not all)
transport functions
- channels and pores ( small water-soluble molecules or ions)
- or can act as carriers ( bind to substance and move it through)
also help stabalize
What is a peripheral membrane protein? - Answers✔not usually embedded
- attached to integral
- or have hydrophobic regions anchored to membrane
3
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