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ABGC Boards Prenatal Study Set Questions and Answers 100% Pass
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ABGC Boards Prenatal Study Set Questions and Answers 100% Pass T21 Risk by Maternal Age - ANSWER -Age-------------------------------Risk 30 --------------------------------1/952 (.1%) 35 --------------------------------1/385 (.3%) 37 --------------------------------1/227 (.4%) 40 ------------...

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  • December 19, 2024
  • 29
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • abgc boards prenatal study set questions and answe

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  • ABGC
  • ABGC

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GraceAmelia

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ABGC Boards Prenatal Study Set Questions and
Answers 100% Pass


T21 Risk by Maternal Age - ANSWER ✔✔-Age-------------------------------Risk


30 --------------------------------1/952 (.1%)


35 --------------------------------1/385 (.3%)


37 --------------------------------1/227 (.4%)


40 --------------------------------1/106 (.9%)


43 --------------------------------1/50 (3.1%)


Risk of Any Chrom Abnl by Maternal Age - ANSWER ✔✔-Age--------------------------------Risk


30---------------------------------1/384 (0.3%)


35---------------------------------1/202 (0.5%)


37---------------------------------1/129 (0.8%)


40---------------------------------1/65 (1.6%)


43---------------------------------1/32 (3.1%)


Maternal Serum Quad Screen - ANSWER ✔✔-Measurement of biochemical analytes in maternal serum to

provide adjusted risk for certain conditions.




Performed during second trimester typically 14-21 weeks




Created by Grace Amelia © 2025, All Rights Reserved.

,2|Page


SLO vs XL ichthyosis,




SLO has pre and postnatal growth restrictions - ANSWER ✔✔-Differentials for extremely low uE3 on

QUAD screen and how can you differentiate


Non-disjunction in Meiosis I - ANSWER ✔✔-What is the most common cause of aneuploidy


Quad screen conditions - ANSWER ✔✔--Open Neural tube defects


- Down Syndrome


- Trisomy 18


Quad screen analytes - ANSWER ✔✔--AFP (alpha-fetoprotein)




-hCG (human chorionic gonadotrophin):




-uE3 (unconjugated estriol):




- Inhibin


Factors to take into account for Quad Screen - ANSWER ✔✔-Gestational Age: As this changes so does

expected values of each analyte




Weight: as maternal weight increases so does blood volume. Dilutes analytes




Created by Grace Amelia © 2025, All Rights Reserved.

, 3|Page


Race: Different ethnic backgrounds can affected expected levels


- i.e. African American ancestry tend to have higher AFP levels




-Diabetic status: insulin dependent diabetics tend to have lower AFP


Effects of inaccurate dating for Quad Screen - ANSWER ✔✔--Overestimate (believe pregnancy is further

along) can lead to false positive for Down syndrome. (Overestimate brings you down)




- Underestimate (reported to be earlier than it is) leads to false positive for NTD. London (The under is

the tubes)




- Generally use first trimester ultrasound for dating rather than LMP


IgM (Most recent)




IgG (It is gone) - ANSWER ✔✔-You see IgM but not IgG is this more concerning for recent infections due

to maternal infection.




Memory device


Estriol and hCG low but AFP high early




All low: Late - ANSWER ✔✔-Patterns for recent and older fetal demise




Created by Grace Amelia © 2025, All Rights Reserved.

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