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2024_OCR - GCSE Biology B (Twenty First Century Science) Depth in Biology (Higher Tier) – Merged Question Paper & Marking Scheme (Friday 7 June 2024 – Afternoon) Code: J257/04 Oxford Cambridge and RSA £6.70
2024_OCR - GCSE Biology B (Twenty First Century Science) Depth in Biology (Higher Tier) – Merged Question Paper & Marking Scheme (Friday 7 June 2024 – Afternoon) Code: J257/04 Oxford Cambridge and RSA
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Module
2024_OCR - GCSE Biology B (Twenty First Century
Institution
2024_OCR - GCSE Biology B (Twenty First Century
2024_OCR - GCSE Biology B (Twenty
First Century Science)
Depth in Biology (Higher Tier) –
Merged Question Paper & Marking
Scheme
(Friday 7 June 2024 – Afternoon)
Code: J257/04
Oxford Cambridge and RSA
Friday 7 June 2024 – Afternoon
GCSE (9–1) Biology B (Twenty First Centur...
2024_OCR - GCSE Biology B (Twenty
First Century Science)
Depth in Biology (Higher Tier) –
Merged Question Paper & Marking
Scheme
(Friday 7 June 2024 – Afternoon)
Code: J257/04
, Oxford Cambridge and RSA
Friday 7 June 2024 – Afternoon
GCSE (9–1) Biology B (Twenty First Century Science)
J257/04 Depth in Biology (Higher Tier)
Time allowed: 1 hour 45 minutes
You must have:
H
* 1 3 7 6 0 3 0 3 1 3 *
• a ruler (cm/mm)
You can use:
• an HB pencil
• a scientific or graphical calculator
* J 2 5 7 0 4 *
Please write clearly in black ink. Do not write in the barcodes.
Centre number Candidate number
First name(s)
Last name
INSTRUCTIONS
• Use black ink. You can use an HB pencil, but only for graphs and diagrams.
• Write your answer to each question in the space provided. If you need extra space use the
lined pages at the end of this booklet. The question numbers must be clearly shown.
• Answer all the questions.
• Where appropriate, your answer should be supported with working. Marks might
be given for using a correct method, even if your answer is wrong.
INFORMATION
• The total mark for this paper is 90.
• The marks for each question are shown in brackets [ ].
• Quality of extended response will be assessed in questions marked with an asterisk (*).
• This document has 20 pages.
ADVICE
• Read each question carefully before you start your answer.
, Oxford Cambridge and RSA - GCSE (9–1) Biology B (Twenty First Century Science) Exam
Overview
Exam Date: Friday, 7 June 2024 – Afternoon Session
Exam Code: J257/04 Depth in Biology (Higher Tier)
The GCSE Biology B (Twenty First Century Science) J257/04 Depth in Biology exam for the
Higher Tier assesses students’ in-depth understanding of more complex biological concepts. It requires
a deeper level of analysis and application of biological knowledge to various scientific situations.
Students will need to demonstrate a thorough grasp of advanced biological principles and their ability
to critically assess biological data and scenarios.
Key Topics and Themes:
1. Cell Biology
o Cell Specialisation and Differentiation: Understanding how cells become specialised
to perform specific functions and the role of stem cells in differentiation.
o Enzyme Action: A deeper understanding of enzymes as biological catalysts, how they
work, the factors that affect their activity (temperature, pH), and their importance in
metabolic reactions.
o Cell Transport Mechanisms: Detailed understanding of passive (diffusion, osmosis)
and active transport, and how these processes facilitate the movement of substances
across cell membranes.
2. Organisation and the Human Body
o Tissues and Organs: Understanding the structure and function of different tissues in
animals and plants, including the role of epithelial, muscle, and connective tissues in the
human body.
o Homeostasis: The mechanisms the body uses to maintain a stable internal environment,
such as the regulation of blood glucose, body temperature, and water balance.
o The Nervous System: Detailed knowledge of how the nervous system works, including
synapses, neurotransmitters, reflex actions, and the central nervous system.
o Endocrine System and Hormonal Control: The function of various glands (e.g.,
pancreas, thyroid, adrenal) and how hormones control vital processes such as
metabolism, growth, and reproduction.
3. Bioenergetics
o Aerobic and Anaerobic Respiration: Understanding the differences between aerobic
respiration (involving oxygen) and anaerobic respiration (involving glucose breakdown
without oxygen), their efficiency, and their implications for energy production in
organisms.
o Photosynthesis and Plant Growth: In-depth study of the photosynthetic process,
including the light-dependent and light-independent stages, and the factors that affect
the rate of photosynthesis in plants.
o Metabolism and Energy Transfer: Understanding how energy is transferred and used
in biochemical reactions and the role of metabolic pathways in maintaining cellular
functions.
4. Infection and Response
o Pathogens and Disease: The biology of pathogens, including bacteria, viruses, fungi,
and protozoa, their methods of causing disease, and how the immune system defends
the body.
o Immunisation and Vaccines: The principles of immunity, including natural immunity
and vaccination, and how vaccines help to protect individuals and populations from
infectious diseases.
o Antibiotic Resistance: How bacteria develop resistance to antibiotics through mutation
and natural selection, and the consequences for public health.
5. Ecology and the Environment
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