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Exam (elaborations)

WS T lymphocyte development MCQs Questions and Answers

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WS T lymphocyte development MCQs Questions and Answers What components are required to successfully engage a TCR? Free protein Peptide bound by a MHC molecule Free peptide Polysaccharide bound by a MHC molecule Protein bound by a MHC molecule Free polysaccharide Peptide bound by a MHC molec...

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  • January 3, 2025
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WS T lymphocyte development MCQs
Questions and Answers
What components are required to successfully engage a TCR?
Free protein
Peptide bound by a MHC molecule
Free peptide
Polysaccharide bound by a MHC molecule
Protein bound by a MHC molecule
Free polysaccharide - answer Peptide bound by a MHC molecule

Question 2
pts
Which thymocyte receptor is critical for early T lymphocyte development?
IL-6 receptor
IL-12 receptor
IL-4 receptor
IL-7 receptor
IL-1 receptor - answer IL-7 receptor

Question 3
pts
Which of the following cells are devoid of MHC-I molecules?
Erythrocyte
Dendritic cell
Epithelial cell
B lymphocyte
Macrophage - answer Erythrocyte

Question 4
pts
At which stage do double-positive thymocytes arise?
Following positive selection
Upon Notch1 ligand stimulation
Upon the formation of the pre-TCR
Upon the formation of a functional TCR a-chain
Upon IL-7 stimulation - answer Upon the formation of the pre-TCR

Question 5
pts
VJ and VDJ TCR chain gene rearrangement is dependent on which enzyme?
AID (activation-induced cytidine deaminase)
ADA (adenosine deaminase)

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