A comprehensive guide spanning over 100 pages on Biochemistry, designed to cater to both enthusiasts and those seeking to strengthen their understanding of these complex subjects. Explore the detailed Table of Contents to ensure it covers the topics you’re looking for.
Main Classes of Biological Molecules
Biological Macromolecules
Aldose vs Ketose Sugars
Isomers of Glucose
Glycosidic Bonds
Amino Acids & Peptide Bonds
Lipids
Nucleic Acids
Protein Folding
Protein Shape Importance
Lipids and Membranes 1
Cell Concept
Major Components of Cell Membranes
Naming & Recognising Lipid Classes and Common Fatty Acids
Unsaturation in Fatty Acids
Membrane Fluidity
Lipid Bilayer Permeability
Protein Structure 2
Functional Role if Proteins in Living Systems
Amino acid and Optical Isomerism
Classification of Amino acids by side chains
Primary Structure
N—terminal, C—terminal, Peptide Bond, Polypeptide
Properties of the Peptide bond & Implications for folding
Ramachandran Plot in protein structure
Cysteine Special properties
Protein Structure II 2
Hierarchical Nature of Protein Structure
Main features of the Hydrogen bond
Principle features of the Alpha—helix and Beta—Sheet structures
Hydrogen bonds between Nitrogen and Oxygen of Peptide Bonds
DNA as a Genetic Material 3
Evidence that DNA transmits Genetic Material
Structure of Double—Stranded Helical DNA (B Form)
Nitrogen Bases: Structure & Classification
Sugar—Phosphate Structure
DNA in Eukaryotic and Prokaryotic Cells
,DNA Replication 40
DNA Replication Mechanism in Prokaryotes
Proof Reading and Error Correction
Eukaryotic vs Prokaryotic Replication
Transcription— Protein Synthesis I 49
Transcription in Prokaryotes
Eukaryotic vs Prokaryotic Transcription
RNA Processing in Eukaryotes
Introns and Exons
Translation— Protein Synthesis II
61
Deciphering the Genetic Code
Codon Structure & Reading Frames
Components of Translation
Amino acid Activation
Translation Stages in Prokaryotes
Eukaryotic vs Prokaryotic Translation
Enzymes I 69
Enzymology Basics
Enzyme Kinetics (Michaelis—Menten)
Interpretation of initial velocity
Michaelis—Menten Model
Enzymes II 76
Enzyme Kinetic Parameter: Competitive and Non-competitive
Inhibition
Allosteric Modulation & Cooperativity
Reversible & Irriversible Inhibition
Mechanisms for Regulation of Enzyme Activity
Introduction to Metabolism 82
Mitochondria
Key Terms
Examples of Anabolic & Catabolic Pathways
Controlled Release of Energy in Enzyme Catalysed Metabolic
Pathways
Activated Carrier Molecules in Energy Metabolism
Functions of Specific Carrier Molecules
ATP as ‘Energy Currency’
, Glucose Metabolism 89
Glucose & Glycogen Structure
Glycolysis
ATP Formation by Substrate Level Phosphorylation
Regenerating NAD+ & the role of lactate dehydrogenase in Muscle
Control Mechanisms in the Regulation of Glycolysis
Role of Glycolysis in different tissues
The TCA Cycle
Pyruvate Dehydrogenase 100
Role of Acetyl—CoA
TCA cycle
Dehydrogenase Enzymes
Oxaloacetate
Biosynthetic Role of the TCA Cycle
Regeneration of Glucose
Oxidative Phosphorylation
112
Electron Carriers
ATP Synthesis
Respiratory Control
Effects of Inhibitors and Uncouplers
ATP Yield
Fat as Fuel
121
Triglycerides for Long—term Fuel Storage
Triglycerides Breakdown
Activation and Transport of Fatty Acids
B—oxidation Pathway
Fatty Acid Oxidation Energy Yield
Regulation or Fatty Acid Oxidation
Metabolism of Odd—numbered Fatty acids
Ketogenesis
Clinical relevance
Nitrogen Metabolism
Nitrogen Balance
130
Protein Degradation
Amino Acid Catabolism
The Urea Cycle
Transport of Ammonia
Carbon Skeleton Metabolism
Essential vs Non—Essential Amino Acids
Roles of Key Amino acids
Clinical Relevance
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