Lecture notes
Notes for clinical applications of biomedical science
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- Keele University (KU)
Notes for module of clinical applications of biomedical science, first year module.
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7th October 2019LECTURE 1- PHYSIOLOGY AND ANATOMY
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LECTURE 1- CLINICAL APPLICATIONS OF BIOMEDICAL SCIENCE
There are many different fields of biomedical sciences that allow for a diagnosis to be made. This
involves branches such as cytology and histopathology in which diseased tissues are observed and
assessed in order to give an accurate report for referring clinicians.
The histo in histopathology refers to the study of tissue, pathology pertains to that of disease
whilst the cyto in cytology means anything relating to the study of cells. Remember cytoplasm is the
part of cells which gives it structure.
there are many different structural changes that can occur in cells that can be picked up upon the
studying of tissue sample.
Types of biopsies
currettings – biopsies obtained by scraping e.g. endometrium, skin, bone.
pipelle – samples taken from endometrium, using a needle
core biopsies – samples taken using a large bore needle (how representative is it of the whole
organ? Very small sample taken)
cone biopsies – complete removal of the squamocolumnar junction of the cervix
Excision – complete removal of diseased tissue with a margin of healthy tissue surrounding it
amputation – the removal of extremity such as an arm or leg
resection – the complete surgical removal of diseased tissue with a margin of healthy tissue
surrounding it
shave biopsy – the removal of tissue via shaving of a lesion
incision – biopsy conducted using a scalpel
endoscopic biopsy – biopsy conducted using an endoscope
Punch biopsy – using an instrument similar to that of a hole punch to obtain a round disc of skin
Assessment:
Clinical case report (25%)
- Wilsons disease; primary tuberculosis; rheumatoid arthritis; pernicious anaemia
Case-based report (25%)
- Mesothelioma; liver disease; HIV; sepsis
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