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Lecture notes

Cell Cycle Notes

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PDF file containing notes from Cell Cycle lecture from the Cells to Systems Module in Pharmacology. Has diagram explaining the cell control mechanisms. Content is for A-level students

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  • January 19, 2025
  • 5
  • 2024/2025
  • Lecture notes
  • David rusling
  • All classes
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Cell Cycle
Created @December 2, 2024 9:44 PM

Class Cells to Systems

Cell cycle

Instructions for producing cell parts

DNA must be replicated

Every new cell has identical copy of DNA

Mechanisms in place to ensure copies are identical



Interphase

G1

Cell grows larger

more organelles are produced

“Checkpoint” is established

Ensures no damage is present

S Phase

Rapid DNA replication and duplication of the centrosome for DNA
separation

G2

Cell increases in size

reorganises cell contents

checks for DNA structure



Cell Cycle 1

, Mitosis

Nuclear division

Cytokinesis
Cells moving apart



Mitosis

Cell division producing two identical cells

Daughter cell gets perfect cell of chromosomes

Too few/ too many chromos can lead to improper function in cells



Mitosis Steps

Early prophase- Chromosome division, and chromos begin to condense

Late prophase/ prometaphase- Spindle organises chromosomes which are
very compact, nuclear envelope breaks down

Metaphase- Chromosomes align on the centre line and attach to spindle
fibres from opposite sides

Anaphase- Chromatids are separated and pulled to opposite ends of the
cell

Telophase- Cell has nearly completed dividing and normal structures
come to be

Cytokinesis- Cytoplasm splits and produces two new cells



Quiescence- No cell cycle occurring but process can happen
Senescence- Cells divided too many times, it has reached its limit



Cells Stop Replicating

Hayflick Limit- Limitation on human cell division



Cell Cycle 2

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