Lecture notes
Chemical Modification and Effect of pH Notes
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- University Of Portsmouth (UoP)
PDF containing notes from the Chemical Modification lecture for Pharmacology
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🍕Chemical Modification and
Effect of pH
Created @January 20, 2025 5:51 PM
Class Molecules to Medicine
H0- Hydrophilic Groups
Carboxylic groups are polar
Aromatic groups are non polar
Hydroxyl groups are polar
Antilog- 10 to the power of pH
Manipulating the Solubility of a Drug
Use of co-solvents (Selecting the right solvent)
Salt formation
Adding solubilising groups to the structure
Using effects of pH
Using dosage forms
Incorporating Water Solubilising Groups
Types of group added
If reaction is reversible or irreversible
Introducing chemical routes
Chemical Modification and Effect of pH 1
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