Summary
Summary Robbins Basic Pathology - Chapter 10
- Module
- Institution
- Book
Summary Chapter 10 - Blood Vessels from Robbins Basic Pathology. Is mainly about Atherosclerosis
[Show more]
Connected book
Book Title:
Author(s):
- Edition:
- ISBN:
- Edition:
More summaries for
-
Test Bank for Robbins Basic Pathology 10th Edition by Vinay Kumar, Abul K. Abba & Jon C. Aster 9780323353175 Chapter 1-24 | Complete Guide A+
-
Test Bank for Robbins Basic Pathology 10th Edition by Vinay Kumar, Abul K. Abba & Jon C. Aster 9780323353175 Chapter 1-24 | Complete Guide A+
-
Test Bank for Robbins Basic Pathology 10th Edition by Vinay Kumar, Abul K. Abba & Jon C. Aster 9780323353175 Chapter 1-24 | Complete Guide A+
1 review
By: Sanjana0511 • 2 year ago
Seller
Followsachajacobs
Reviews received
Content preview
Chapter 10 – Blood VesselsArteriosclerosis
Arteriosclerosis literally means ‘hardening of the arteries’; is a generic term reflecting
arterial wall thickening and loss of elasticity. Four distinct types are recognized:
Arteriosclerosis affects the small arteries and arterioles and may cause downstream
ischemic injury
Mönckeberg medial sclerosis is characterized by the presence of calcific deposits in
muscular arteries.
Fibromuscular intimal hyperplasia is a non-atherosclerotic process that occurs in
muscular arteries larger than arterioles.
Atherosclerosis is the most frequent and clinically important pattern.
Atherosclerosis
Atherosclerosis is characterized by intimal lesions called atheroma’s (or atheromatous or
atherosclerotic plaques) that impinge on the vascular lumen and can rupture to cause
sudden occlusion. Atheromatous plaques are raised lesions composed of soft friable lipid
cores, covered by fibrous caps. As they enlarge, atherosclerotic plaques may mechanically
obstruct vascular lumina, leading to stenosis. Atherosclerotic plaques also are prone to
rupture, an event that may result in thrombosis and sudden occlusion of the vessel.
Epidemiology of atherosclerosis
The prevalence and severity of atherosclerosis and IHD have been correlated with a number
of risk factors.
Constitutional Risk Factors
Genetics
o Mendelian disorders
Age
o Usually remains clinically silent until lesions reach a critical threshold in
middle age or later
Gender
o Premenopausal: relatively less women
o Postmenopausal: could exceed men
Modifiable Major Risk Factors
Hyperlipidemia/ hypercholesterolemia
o Major risk factor for development of atherosclerosis and is sufficient to
induce lesions in the absence of other risk factors
o Lower LDL or increase HDL
High dietary intake of cholesterol
Omega-3 fatty acids
Exercise
Statins
Hypertension
o Increase risk for IHD
Cigarette smoking
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller sachajacobs. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £3.42. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
67474 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now