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Exam (elaborations)

Pharmaceutical Calculations

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This document contains pharmaceutical calculations which is very helpful for beginners on pharmacy role

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  • January 26, 2021
  • 4
  • 2019/2020
  • Exam (elaborations)
  • Questions & answers
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PAST QUESTIONS ON PHARMACEUTICAL CALCULATIONS




1. You are asked to prepare 0.5L of a solution of magnesium carbonate that has
a concentration of 0.12g/15ml for the treatment of magnesium deficiency. You
have available in the dispensary vial containing 0.75g of magnesium
carbonate that will dissolve in 50ml of water.
What volume of the vial solution (in ml) will you need to prepare the
0.12g/15ml solution?

Answer
15/1000 = 0.015
(0.5/0.015) x 0.12 = 4
4 x (50/0.75) = 267

Ans: 267 ml


2. Dr Singh who works at the nearby GP practice phones you with a request for
some help.
He has a patient that is suffering from a fungal skin infection on the skin
around the base of their legs and wishes for them to soak their legs in a
suspended solution of miconazole.
Dr Singh would like to create a solution that has a total volume of 80ml. When
18ml of this solution is diluted to 1 litre the resulting solution is 1 in 5000 w/v.

What weight (in mg) of miconazole is required to make the solution?

Answer
1 in 5000
1000mg in 5000ml
x in 1000ml x = 200 mg (cross-multiply)
200 mg in 18 ml
80/18 = 4
4 x 200 = 888.8 = 889

Ans: 889 mg

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