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Lecture notes on biological rhythms covering: lesion studies, brain stem control of sleep and wakefulness (Bremner, 1937), reticular formation, brain mechanisms of sleep and waking, neurotransmitters and sleep, sleep-wake switch, flip-flop switch, the sleep switch, biological clocks and brain areas, genes and rhythms, chronotype variations, why light is important, two process theory (Borbely, 1974), effects of sleep disruption, and classification of sleep disorders.